Mouse LIFR (Leukemia Inhibitory Factor Receptor) CLIA Kit
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Catalog numberE-CL-M0478-96T
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Price:
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Size96Test
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Detection TypeColormetric
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Target SpeciesMouse
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Target SynonymCD118, LIF-R, SJS2, STWS, SWS
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Test principleThis CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Mouse LIFR . Standards or samples are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse LIFR and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse LIFR , biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of Mouse LIFR . You can calculate the concentration of Mouse LIFR in the samples by comparing the RLU value of the samples to the standard curve.
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Sensitivity7.5pg/mL
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Detection Range12.5~800pg/mL
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Target NameLIFR
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UNIProt IDNA
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Tested Sample TypesSerum, Plasma, Cell supernatant
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Product NameMouse LIFR (Leukemia Inhibitory Factor Receptor) CLIA Kit
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TypeSandwich
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolLIFR-AS1, LIFR
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Short nameMouse LIFR (Leukemia Inhibitory Factor Receptor) CLIA Kit
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TechniqueMouse, mouses
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Hostmouse
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SpeciesMouse, Mouses
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Alternative nameMouse leukemia inhibitory factor receptor alpha (Leukemia Inhibitory Factor Receptor) CLIA reagent
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Alternative techniquemurine, kits
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Alternative to gene targetleukemia inhibitory factor receptor alpha, CD118 and LIF-R and SJS2 and STWS and SWS, LIFR and IDBG-17489 and ENSG00000113594 and 3977, growth factor binding, Extracellular, Lifr and IDBG-128297 and ENSMUSG00000054263 and 16880, LIFR and IDBG-630017 and ENSBTAG00000010423 and 539504
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Virusleukemia
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Gene info
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Identity
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Gene
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Long gene nameLIFR antisense RNA 1
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Synonyms gene name
- LIFR antisense RNA 1 (non-protein coding)
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GenBank acession
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Locus
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Discovery year2011-11-23
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Entrez gene record
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Pubmed identfication
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameLIF receptor subunit alpha
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Synonyms gene name
- leukemia inhibitory factor receptor
- leukemia inhibitory factor receptor alpha
- LIF receptor alpha
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-08-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibronectin type III domain containing
- CD molecules
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
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Tree numbers
- C04.557.337.372
- C04.619.531
- E05.598.500.496.500
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Qualifiersdiagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery