Rabbit Anti Human DDX42 Antibody-Non-conjugated

• Catalog number
  CSB-PA773053LA01HU_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Human DDX42, Non-conjugated
• Synonym name
  DDX42 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,IHC;Recommended dilution:IHC:1:20-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  Q86XP3
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant human ATP-dependent RNA helicase DDX42 protein (519-819AA)
• Immunogen species
  Human
• Alias
  ATP-dependent RNA helicase DDX42 (EC:3.6.4.13),DDX42,DEAD box protein 42,RNA helicase-like protein,RHELP,RNA helicase-related protein,RNAHP,SF3b DEAD box protein,Splicing factor 3B-associated 125 kDa protein,SF3b125
• Background
  ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.
• Clonality
  Polyclonal antibody
• Shipping and storage
  DDX42 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  DDX42   Non-conjugated  
• Gene symbol
  DDX42
• Short name
  Anti-DDX42
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  DDX42 Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  DEAD (Asp-Glu-Ala-Asp) box polypeptide 42, DDX42P and RHELP and RNAHP and SF3b125 and SF3B8, DDX42 and IDBG-63647 and ENSG00000198231 and 11325, poly(A) RNA binding, nuclei, Ddx42 and IDBG-213407 and ENSMUSG00000020705 and 72047, DDX42 and IDBG-641673 and ENSBTAG00000021058 and 100140430

Gene info

• Identity
  HGNC:18676
• Gene
  DDX42
• Long gene name
  DEAD-box helicase 42
• Synonyms gene name
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
  • DEAD (Asp-Glu-Ala-Asp) box helicase 42
• Synonyms
  • RNAHP
  • RHELP
  • SF3b125
  • SF3B8
• Synonyms name
  • splicing factor 3b, subunit 8
• GenBank acession
  • BC015505
• Locus
  17q23.3
• Discovery year
  2003-06-13
• Entrez gene record
  11325
• Pubmed identfication
  • 10727850
  • 16397294
• RefSeq identity
  • NM_007372
• Classification
  • DEAD-box helicases
• VEGA ID
  OTTHUMG00000179011

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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