Mouse Single Ig IL-1-related receptor (Sigirr)

  • Catalog number
    CSB-EP888356MO-10ug
  • Price
    Please ask
  • Size
    10ug
  • Description
    Recombinant Mouse Single Ig IL-1-related receptor(Sigirr),partial expressed in E.coli
  • Specifications
    Uniprot ID: Q9JLZ8; Host: Mus musculus (Mouse); Expression system: E.coli; Expression region: 1-117aa; Sequence information: Partial; Tag: N-terminal 6xHis-SUMO-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
  • Additional_information
    MW: 28.7 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
  • Storage_and_shipping
    Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
  • Notes
    For research use only.
  • Gene
    The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Additional description
    The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
  • Gene symbol
    IL1A, IL1B, IL1F10, IL36B, IL36A, IL19, IL17F, IL36G, IL25, IL22
  • Short name
    Mouse Single Ig IL-1- receptor (Sigirr)
  • Technique
    Mouse, mouses
  • Host
    mouse
  • Species
    Mouse, Mouses
  • Alternative name
    Mouse Single Ig Interleukin-1-related receptor (single immunoglobulin and toll-interleukin 1 receptor (TIR) domain)
  • Alternative technique
    murine
  • Alternative to gene target
    single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, SIGIRR and IDBG-16551 and ENSG00000185187 and 59307, protein binding, Plasma membranes, Sigirr and IDBG-211977 and ENSMUSG00000025494 and 24058, SIGIRR and IDBG-645604 and ENSBTAG00000011149 and 531801
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