Human Thrombopoietin receptor (MPL)
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Catalog number
CSB-EP014755HU-200ug
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Price
Please ask
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Size
200ug
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Description
Recombinant Human Thrombopoietin receptor(MPL),partial expressed in E.coli
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Specifications
Uniprot ID: P40238; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 26-491aa; Sequence information: Extracellular Domain; Tag: N-terminal 6xHis-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
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Additional_information
MW: 56.5 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
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Storage_and_shipping
Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
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Notes
For research use only.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
MPL
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Short name
Thrombopoietin receptor (MPL)
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Species
Human, Humans
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Alternative name
H. sapiens Thrombopoietin receptor (myeloproliferative leukemia virus oncogene)
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Alternative to gene target
myeloproliferative leukemia virus oncogene, C-MPL and CD110 and MPLV and THCYT2 and TPOR, MPL and IDBG-97403 and ENSG00000117400 and 4352, protein binding, Plasma membranes, Mpl and IDBG-181592 and ENSMUSG00000006389 and 17480, BT.26255 and IDBG-640482 and ENSBTAG00000003781 and 528492
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Gene info
Product images
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