Thrombopoietin Receptor (TPO-R, Myeloproliferative Leukemia Protein, Proto-oncogene c-Mpl, CD110, TPOR)
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Catalog numberMBS629909
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PricePlease ask
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Size0,1 mg
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Other sizeplease contact us to order other different size
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolMPL, TPO, THPO, RRAS, DAD1P1, HNRNPR, CLDN4, MC1R, CTNNA2, PTPRK
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Short nameThrombopoietin Receptor (TPO-R, Myeloproliferative Leukemia Protein, Proto-oncogene c-Mpl, CD110, TPOR)
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Alternative nameThrombopoietin Receptor (TPO-R, Myeloproliferative Leukemia Protein, Proto-oncogene c-myeloproliferative leukemia virus oncogene, CD110, TPOR)
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Alternative to gene targetmyeloproliferative leukemia virus oncogene, C-MPL and CD110 and MPLV and THCYT2 and TPOR, MPL and IDBG-97403 and ENSG00000117400 and 4352, protein binding, Plasma membranes, Mpl and IDBG-181592 and ENSMUSG00000006389 and 17480, BT.26255 and IDBG-640482 and ENSBTAG00000003781 and 528492
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Virusleukemia
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Gene info
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Identity
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Gene
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Long gene nameMPL proto-oncogene, thrombopoietin receptor
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Synonyms gene name
- myeloproliferative leukemia virus oncogene
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-09-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibronectin type III domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namethyroid peroxidase
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Synonyms
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Locus
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Discovery year1986-01-01
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Entrez gene record
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RefSeq identity
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Classification
- Sushi domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namethrombopoietin
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Synonyms gene
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-11-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameRAS related
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Synonyms gene name
- related RAS viral (r-ras) oncogene homolog
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedefender against cell death 1 pseudogene 1
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Synonyms gene
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Synonyms gene name
- defender against cell death 1-like
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Synonyms
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Locus
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Discovery year2007-07-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene nameheterogeneous nuclear ribonucleoprotein R
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-06-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Heterogeneous nuclear ribonucleoproteins
- RNA binding motif containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameclaudin 4
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Claudins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemelanocortin 1 receptor
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Synonyms gene name
- melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Melanocortin receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecatenin alpha 2
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Synonyms gene name
- catenin (cadherin-associated protein), alpha 2
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-07-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Alpha catenins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase receptor type K
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-02-09
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Entrez gene record
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Pubmed identfication
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Classification
- Protein tyrosine phosphatases receptor type
- Fibronectin type III domain containing
- Immunoglobulin like domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
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Tree numbers
- C04.557.337.372
- C04.619.531
- E05.598.500.496.500
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Qualifiersdiagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery
