100ug-Anti-Caspase Activated DNase (CAD)

Organism Species

Homo sapiens (Human)
Source

Polyclonal antibody preparation
Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Item Name

Caspase Activated DNase
Immunogen

RPB058Hu01-Recombinant Caspase Activated DNase (CAD)
Image number

2
Species reactivity

Human
Sequence of immunogen

CAD (Arg87~Lys323)
Aplication

WB,IHC
Clonality

Rabbit polyclonal
Concentration

500ug/ml
Alternative Names

DFF-B; DFFB; CPAN; DFF40; DFF2; DNA Fragmentation Factor 40kDa Beta Polypeptide; Caspase-activated deoxyribonuclease; Caspase-activated nuclease
Applicable Secondary Antibody

SAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
Manual link
Delivery condition

4℃ with ice bags
Storage instructions

Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

Identity

HGNC:1424
Gene

CAD
Long gene name

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Synonyms
- GATD4
GenBank acession
- D78586
Locus

2p23.3
Discovery year

2001-06-22
Entrez gene record

790
Pubmed identfication
- 8619816
- 2565865
Classification
- Glutamine amidotransferase class 1 domain containing
VEGA ID

OTTHUMG00000097070

Identity

HGNC:24136
Gene

B4GALNT2
Long gene name

beta-1,4-N-acetyl-galactosaminyltransferase 2
Synonyms gene
- GALGT2
Synonyms gene name
- UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase
Synonyms
- Sda
- Cad
GenBank acession
- AJ517770
Locus

17q21.32
Discovery year

2004-02-20
Entrez gene record

124872
Pubmed identfication
- 8782649
- 12678917
RefSeq identity
- NM_153446
Classification
- Beta 4-glycosyltransferases
VEGA ID

OTTHUMG00000161307

Identity

HGNC:1752
Gene

CDH12P2
Long gene name

cadherin 12 pseudogene 2
Synonyms gene
- CDH12P
Synonyms gene name
- cadherin 12 (N-cadherin 2) pseudogene
- cadherin 12 (N-cadherin 2) pseudogene 2
Synonyms
- C41-CAD
GenBank acession
- AC004999
Locus

5q13.2
Discovery year

1995-11-30
Entrez gene record

1011
Pubmed identfication
- 7731968
- 10369862
VEGA ID

OTTHUMG00000162392

Identity

HGNC:2773
Gene

DFFB
Long gene name

DNA fragmentation factor subunit beta
Synonyms gene name
- DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
Synonyms
- CAD
- CPAN
- DFF-40
- DFF40
Synonyms name
- caspase-activated DNase
Locus

1p36.32
Discovery year

1997-10-27
Entrez gene record

1677
Pubmed identfication
- 9108473
- 9560346
RefSeq identity
- NM_001282669
VEGA ID

OTTHUMG00000003525

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data