Biotin-Linked Antibody to Caspase Activated DNase (CAD)

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Properties

If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Conjugation

Biotinylated
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
French translation

anticorps

Gene target

Linked Caspase Activated DNase CAD
Gene symbol

CALD1, CAD, B4GALNT2, ACOD1, CDH12P2, DFFB
Short name

-Linked Antibody Caspase Activated DNase (CAD)
Technique

Antibody, antibodies against human proteins, antibodies for
Label

Biotin
Alternative name

biotinilated-Linked (antibody to-) to caspase Activated DNase (CAD)
Alternative technique

antibodies

Identity

HGNC:1424
Gene

CAD
Long gene name

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Synonyms
- GATD4
GenBank acession
- D78586
Locus

2p23.3
Discovery year

2001-06-22
Entrez gene record

790
Pubmed identfication
- 8619816
- 2565865
Classification
- Glutamine amidotransferase class 1 domain containing
VEGA ID

OTTHUMG00000097070

Identity

HGNC:24136
Gene

B4GALNT2
Long gene name

beta-1,4-N-acetyl-galactosaminyltransferase 2
Synonyms gene
- GALGT2
Synonyms gene name
- UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase
Synonyms
- Sda
- Cad
GenBank acession
- AJ517770
Locus

17q21.32
Discovery year

2004-02-20
Entrez gene record

124872
Pubmed identfication
- 8782649
- 12678917
RefSeq identity
- NM_153446
Classification
- Beta 4-glycosyltransferases
VEGA ID

OTTHUMG00000161307

Identity

HGNC:1752
Gene

CDH12P2
Long gene name

cadherin 12 pseudogene 2
Synonyms gene
- CDH12P
Synonyms gene name
- cadherin 12 (N-cadherin 2) pseudogene
- cadherin 12 (N-cadherin 2) pseudogene 2
Synonyms
- C41-CAD
GenBank acession
- AC004999
Locus

5q13.2
Discovery year

1995-11-30
Entrez gene record

1011
Pubmed identfication
- 7731968
- 10369862
VEGA ID

OTTHUMG00000162392

Identity

HGNC:2773
Gene

DFFB
Long gene name

DNA fragmentation factor subunit beta
Synonyms gene name
- DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
Synonyms
- CAD
- CPAN
- DFF-40
- DFF40
Synonyms name
- caspase-activated DNase
Locus

1p36.32
Discovery year

1997-10-27
Entrez gene record

1677
Pubmed identfication
- 9108473
- 9560346
RefSeq identity
- NM_001282669
VEGA ID

OTTHUMG00000003525

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data