SMURF1 Antibody

• Catalog number
  PB9892
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  SMURF1
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence in the middle region of human SMURF1 (326-351aa DHNNRTTQFTDPRLHHIMNHQCQLKE), identical to the related mouse sequence.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the SMURF1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The SMURF1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  E3 ubiquitin-protein ligase SMURF1 is an enzyme that in humans is encoded by the SMURF1 gene. It is mapped to 7q22.1. This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Related articles
  1. "Entrez Gene: SMURF1 SMAD specific E3 ubiquitin protein ligase 1". 2. Yamaguchi K, Ohara O, Ando A, Nagase T (Apr 2008). "Smurf1 directly targets hPEM-2, a GEF for Cdc42, via a novel combination of protein interaction modules in the ubiquitin-proteasome pathway". Biol. Chem. 389 (4): 405–13. 3. Zhu H, Kavsak P, Abdollah S, Wrana JL, Thomsen GH (Sep 1999). "A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation". Nature 400 (6745): 687–93.
• Gene Name
  SMURF1
• Protein Name
  E3 ubiquitin-protein ligase SMURF1
• Gene Full Name
  SMAD specific E3 ubiquitin protein ligase 1
• Synonyms
  E3 ubiquitin-protein ligase SMURF1 antibody|hSMURF1 antibody|KIAA1625 antibody|Smad specific E3 ubiquitin ligase 1 antibody|SMAD specific E3 ubiquitin protein ligase 1 antibody|Smad ubiquitination regulatory factor 1 antibody|SMAD-specific E3 ubiquitin-protein ligase 1 antibody|SMUF1_HUMAN antibody|SMURF 1 antibody|smurf1 antibody
• Uniprot ID
  Q9HCE7
• Entrez GeneID
  57154
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SMURF1  
• Gene symbol
  SMURF1
• Short name
  SMURF1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  SMAD specific E3 ubiquitin protein ligase 1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  SMAD specific E3 ubiquitin protein ligase 1, SMURF1 and IDBG-28871 and ENSG00000198742 and 57154, R-SMAD binding, nuclei, Smurf1 and IDBG-208404 and ENSMUSG00000038780 and 75788, SMURF1 and IDBG-640859 and ENSBTAG00000007118 and

Gene info

• Identity
  HGNC:16807
• Gene
  SMURF1
• Long gene name
  SMAD specific E3 ubiquitin protein ligase 1
• Synonyms
  • KIAA1625
• GenBank acession
  • AB046845
• Locus
  7q22.1
• Discovery year
  2004-07-29
• Entrez gene record
  57154
• Pubmed identfication
  • 10458166
• RefSeq identity
  • NM_020429
• Classification
  • HECT domain containing
• VEGA ID
  OTTHUMG00000150272

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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