SMURF1 Antibody
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Catalog numberR32324
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenSMURF1
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB
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Recommended dilutionsWestern blot: 0.1-0.5ug/ml
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NotesOptimal dilution of the SMURF1 antibody should be determined by the researcher.
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Intented useThis SMURF1 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ9HCE7
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PurityAntigen affinity
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DescriptionE3 ubiquitin-protein ligase SMURF1 is an enzyme that in humans is encoded by the SMURF1 gene. It is mapped to 7q22.1. This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.
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ImmunogenAmino acids DHNNRTTQFTDPRLHHIMNHQCQLKE of human SMURF1 were used as the immunogen for the SMURF1 antibody.
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StorageAfter reconstitution, the SMURF1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSMURF1
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Short nameAnti-SMURF1
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to SMURF1
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Alternative techniqueantibodies
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Alternative to gene targetSMAD specific E3 ubiquitin protein ligase 1, SMURF1 and IDBG-28871 and ENSG00000198742 and 57154, R-SMAD binding, nuclei, Smurf1 and IDBG-208404 and ENSMUSG00000038780 and 75788, SMURF1 and IDBG-640859 and ENSBTAG00000007118 and
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Gene info
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Identity
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Gene
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Long gene nameSMAD specific E3 ubiquitin protein ligase 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-07-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- HECT domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data