Recombinant Human CD46/MCP (C-6His)

Alternative names

Membrane Cofactor Protein, TLX, Trophoblast Leukocyte Common Antigen, CD46, MCP, MIC10
Description

Recombinant Human CD46 is produced by our Mammalian expression system and the target gene encoding Cys35-Asp328 is expressed with a 6His tag at the C-terminus.
Expression

Human Cells
Tag

C-His
Endotoxin

Less than 0.1 ng/ug (1 EU/ug)
Accession

P15529
TargetSequence

Cys35-Asp328
Shipping

Ambient
Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Note

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

CD46/MCP C-6His
Gene symbol

CD46, CAPG, CCL8, SLC25A33, CCL7, CCL13, CCR2, CCL2
Short name

Recombinant CD46/MCP (C-6His)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens CD46 molecule, complement regulatory protein/MCP (C-6His)
Alternative technique

rec
Alternative to gene target

CD46 molecule, complement regulatory protein, AHUS2 and MCP and MIC10 and TLX and TRA2.10, CD46 and IDBG-106372 and ENSG00000117335 and 4179, cadherin binding, Cell surfaces, Cd46 and IDBG-209330 and ENSMUSG00000016493 and 17221, BT.68611 and IDBG-638462 and ENSBTAG00000005397 and 280851

Identity

HGNC:6953
Gene

CD46
Long gene name

CD46 molecule
Synonyms gene
- MIC10
- MCP
Synonyms gene name
- antigen identified by monoclonal antibody TRA-2-10
- membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
- CD46 antigen, complement regulatory protein
- CD46 molecule, complement regulatory protein
Synonyms
- TRA2.10
- MGC26544
- TLX
GenBank acession
- BC030594
Locus

1q32.2
Discovery year

1988-08-31
Entrez gene record

4179
Pubmed identfication
- 7929741
RefSeq identity
- NM_172361
Classification
- Sushi domain containing
- Complement system regulators and receptors
- CD molecules
VEGA ID

OTTHUMG00000036397
Locus Specific Databases
- LRG_155

Identity

HGNC:10635
Gene

CCL8
Long gene name

C-C motif chemokine ligand 8
Synonyms gene
- SCYA8
Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
- chemokine (C-C motif) ligand 8
Synonyms
- MCP-2
- HC14
GenBank acession
- X99886
Locus

17q12
Discovery year

1996-11-14
Entrez gene record

6355
Pubmed identfication
- 9119400
RefSeq identity
- NM_005623
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132883

Identity

HGNC:29681
Gene

SLC25A33
Long gene name

solute carrier family 25 member 33
Synonyms gene name
- solute carrier family 25, member 33
- solute carrier family 25 (pyrimidine nucleotide carrier), member 33
Synonyms
- MGC4399
- BMSC-MCP
- PNC1
GenBank acession
- AF495714
Locus

1p36.22
Discovery year

2006-09-21
Entrez gene record

84275
Pubmed identfication
- 14715278
- 16949250
RefSeq identity
- NM_032315
Classification
- Solute carriers
VEGA ID

OTTHUMG00000001322

Identity

HGNC:10634
Gene

CCL7
Long gene name

C-C motif chemokine ligand 7
Synonyms gene
- SCYA6
- SCYA7
Synonyms gene name
- small inducible cytokine A7 (monocyte chemotactic protein 3)
- chemokine (C-C motif) ligand 7
Synonyms
- MCP-3
- NC28
- FIC
- MARC
- MCP3
Synonyms name
- monocyte chemoattractant protein 3
- monocyte chemotactic protein 3
GenBank acession
- AF043338
Locus

17q12
Discovery year

1993-11-04
Entrez gene record

6354
Pubmed identfication
- 8461011
RefSeq identity
- NM_006273
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132889

Identity

HGNC:10611
Gene

CCL13
Long gene name

C-C motif chemokine ligand 13
Synonyms gene
- SCYA13
Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 13
- chemokine (C-C motif) ligand 13
Synonyms
- MCP-4
- NCC-1
- SCYL1
- CKb10
- MGC17134
GenBank acession
- AJ001634
Locus

17q12
Discovery year

1997-02-11
Entrez gene record

6357
Pubmed identfication
- 8661057
RefSeq identity
- NM_005408
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132890

Identity

HGNC:10618
Gene

CCL2
Long gene name

C-C motif chemokine ligand 2
Synonyms gene
- SCYA2
Synonyms gene name
- small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
- chemokine (C-C motif) ligand 2
Synonyms
- MCP1
- MCP-1
- MCAF
- SMC-CF
- GDCF-2
- HC11
- MGC9434
Synonyms name
GenBank acession
- BC009716
Locus

17q12
Discovery year

1990-07-05
Entrez gene record

6347
Pubmed identfication
- 2004761
RefSeq identity
- NM_002982
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132887