RasGAP Antibody

• Catalog number
  3311-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  RasGAP
• Target Alternative Name
  RASGAP, p120GAP , RASA1, RASA, CMAVM, CM-AVM , PKWS , p120GAP, DKFZp434N071
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat, bovine
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 1025 of human RasGAP
• Accession
  P20936
• Gene Id
  5921
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.2 mg/ml
• Formulation
  100 µg (0.2 mg/ml) protein A purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunoprecipitation, Immunohistochemistry
• Application And Usages
  Western blotting (0.5-4 µg/ml) and in immunoprecipitation (10-20 µg/ml) and Immunohistochemistry (10-20 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate can be used as a positive control. The antibody recognizes ~120 kDa Ras GAP of human, mouse, rat, and bovine origins.
• Description
  The mammalian proto-oncogene Ras encodes 21 kDa proteins (p21Ras) which exists in either a physiologically quiescent GDP-binding state or a GTPbinding signal-emitting state. Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold. The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RasGAP  
• Gene symbol
  IQGAP1
• Short name
  RasGAP Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  RasGAP (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6110
• Gene
  IQGAP1
• Long gene name
  IQ motif containing GTPase activating protein 1
• Synonyms
  • p195
  • KIAA0051
  • SAR1
  • HUMORFA01
• Synonyms name
  • RasGAP-like with IQ motifs
• GenBank acession
  • D29640
• Locus
  15q26.1
• Discovery year
  1999-07-23
• Entrez gene record
  8826
• Pubmed identfication
  • 8051149
  • 8670801
• RefSeq identity
  • NM_003870
• Classification
  • IQ motif containing GTPase activating protein family
• VEGA ID
  OTTHUMG00000149832

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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