RasGAP (Ras GTPase Activating Protein, GAP)

Products_type

Antibody
Products_short_name

[RasGAP]
Products_name_syn

[Anti -RasGAP (Ras GTPase Activating Protein, GAP)]
Other_names

[ras GTPase-activating protein 1 isoform 1; Ras GTPase-activating protein 1; ras GTPase-activating protein 1; triphosphatase-activating protein; RAS p21 protein activator (GTPase activating protein) 1; Ras p21 protein activator; p120GAP]
Other_gene_names

[RASA1; RASA1; GAP; PKWS; RASA; CMAVM; CM-AVM; RASGAP; p120GAP; p120RASGAP; RASA; GAP; GTPase-activating protein; RasGAP]
Clonality

Polyclonal
Reactivity

Chicken, Human, Mouse, Rat
Specificity

Recognizes human GAP at 120kD. Species Crossreactivity: Chicken, mouse and rat.
Purity

Affinity Purified Purified by Protein A affinity chromatography.
Form

Supplied as a lyophilized powder from 0.1M Tris-HCl, 0.15M sodium chloride, 0.05% sodium azide. Reconstitute with 200ul sterile distilled water.
Storage_stability

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

Western Blot (WB), Immunoprecipitation (IP)

Identity

HGNC:6139
Gene

ITGA3
Long gene name

integrin subunit alpha 3
Synonyms gene
- MSK18
Synonyms gene name
- antigen identified by monoclonal antibody J143
- integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Synonyms
- CD49c
- VLA3a
- VCA-2
- GAP-B3
Synonyms name
- alpha 3 subunit of VLA-3 receptor
- antigen CD49C
GenBank acession
- M59911
Locus

17q21.33
Discovery year

1992-02-27
Entrez gene record

3675
Pubmed identfication
- 1655803
- 9704023
RefSeq identity
- NM_005501
Classification
- Integrin alpha subunits
- CD molecules
VEGA ID

OTTHUMG00000161890

Identity

HGNC:9871
Gene

RASA1
Long gene name

RAS p21 protein activator 1
Synonyms gene
- RASA
Synonyms gene name
- RAS p21 protein activator (GTPase activating protein) 1
Synonyms
- GAP
- CM-AVM
- p120GAP
- p120RASGAP
- p120
Synonyms name
- capillary malformation-arteriovenous malformation
- p120 RAS GTPase activating protein
Locus

5q14.3
Discovery year

1989-06-30
Entrez gene record

5921
Pubmed identfication
- 15917201
RefSeq identity
- NM_002890
Classification
- SH2 domain containing
- C2 and RasGAP domain containing
- Pleckstrin homology domain containing
VEGA ID

OTTHUMG00000162605
Locus Specific Databases
- SH2base: Database for pathogenic SH2 domain mutations