PicoProbeTM Glutamate Carboxypeptidase II Activity Assay Kit

• Catalog number
  K738-100
• Price
  Please ask
• Size
  100 assays

• Description
  Sensitive assay for the detection and quantification of active Glutamate Carboxypeptidase
• Summary
  Glutamate Carboxypeptidase II Activity Assay Kit: Convenient assay to measure GCPII activity in biological samples. Detection Limit: 0.5 µU.
• Detection Method
  Fluorometric (Ex/Em= 535/587 nm)
• Species Reactivity
  All
• Applications
  Measurement of Glutamate Carboxypeptidase II Activity in Biological Samples/Preparations.
• Sample Type
  Purifed Enzyme/Protein preparations, Tissue lysate
• Features Benefits
  Sensitive assay for measuring GCPII activity in various biological samples., HTS adaptable, Simple procedure, Fast and convenient
• Storage Conditions
  -20°C
• Shipping Conditions
  Gel Pack
• Shelf life
  12 months
• Background
  Glutamate Carboxypeptidase II [GCPII, EC 3.4.17.21; N-acetylated-alpha-linked acidic dipeptidase (NAALADase), prostate-specific membrane antigen (PSMA) or folate hydrolase (FOLH1)] is a zinc-metallopeptidase, multifunctional protein. In humans, it is mainly expressed in the nervous system, prostate, small intestine and kidney. In males, PSMA is overexpressed in patients suffering prostate cancer and thus, it is used as a diagnostic marker for this disease. NAALADase, the brain isozyme, plays an important role in Glutamate biosynthesis and could be used for treating neuronal damage caused by excess glutamate in brain. BioVision’s PicoProbeTM Glutamate Carboxypeptidase II Activity Assay Kit is a simple plate-based fluorometric assay for the measurement of GCPII activity in Biological Samples. The provided substrate is transaminated in the presence of GCPII producing glutamate. The detection system is based on an enzymatic reaction in which a fluorogenic probe is reduced generating a stable signal. The reduced fluorophore produces a strong signal which is directly proportional to the amount of active GCPII in samples. The assay can detect as low as 0.5 µU of Glutamate Carboxypeptidase II.
• Data Sheet Link
• Test
  Biovision supplies other types of Assays as 1.

• Gene target
  PicoProbeTM   Glutamate   Carboxypeptidase   Activity   Kit  
• Short name
  PicoProbeTM Glutamate Carboxypeptidase II Activity Assay Kit
• Technique
  Assay, assays
• Host
  Assay
• Alternative name
  PicoProbeTM Glutamate Carboxypeptidase II Activity test reagent
• Alternative technique
  arrays, kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

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