PicoProbeTM Methylglyoxal Assay Kit (Fluorometric)

  • Catalog number
    K461-100
  • Price
    Please ask
  • Size
    100 assays
  • Description
    First fluorometric kit in the market that can detect Methylglyoxal in samples
  • Summary
    • Detection method- Fluorescence (RFU: 535/587 nm) • Species reactivity- Eukaryotes • Applications- This Kit provides a simple, highly sensitive in vitro assay for detecting Methylglyoxal levels in biological samples.
  • Detection Method
    Fluorescence (Ex/Em 535/587nm)
  • Species Reactivity
    Eukaryotes
  • Applications
    This Kit provides a simple, highly sensitive in vitro assay for detecting Methylglyoxal levels in biological samples.
  • Sample Type
    • Tissue Homogenates and Cell Lysates: Mouse Liver, Rat Brain, Jurkat cells, etc. • Biological Fluids: Cerebrospinal Fluid (CSF), etc.
  • Features Benefits
    This Kit provides a simple, highly sensitive in vitro assay for detecting Methylglyoxal levels in biological samples.
  • Storage Conditions
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf life
    12 months
  • Background
    Methylglyoxal ( mg, 2-oxopropanal, pyruvic aldehyde), a by-product of glycolysis, is a highly toxic, reactive dicarbonyl compound. It causes non-enzymatic glycation of proteins which yields irreversible advanced glycation end products (AGEs), leading to cross-linking or degradation of proteins. mg is associated with several pathologies including diabetes, aging and neurodegenerative diseases. Furthermore, recent studies have suggested that mg may induce carbonyl stress-type schizophrenia. BioVision’s PicoProbeTM Methylglyoxal Assay Kit (Fluorometric) can detect mg using an enzyme-coupled reaction which reduces the fluorogenic probe. The reduced fluorophore produces a stable signal (Ex/Em= 535/587nm), which is directly proportional to the amount of mg in samples. The assay is simple, reproducible and can specifically detect as low as 6 pmol of mg in a 100 µl reaction.
  • Test
    Biovision supplies other types of Assays as 1.
  • Gene target
  • Short name
    PicoProbeTM Methylglyoxal Assay Kit (Fluorometric)
  • Technique
    Assay, assays
  • Host
    Assay
  • Alternative name
    PicoProbeTM Methylglyoxal test reagent (fluorescence)
  • Alternative technique
    arrays, kits
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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