HDAC3 Activity Fluorometric Assay Kit

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• Catalog number
  K343-100
• Price:

  480.3 USD

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• Size
  100 assays

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• Description
  Sensitive Assay, HTS
• Summary
  • Detection method- Fluorescence (Em/Ex = 380/500 nm) • Applications- Suitable for high throughput measurement of HDAC3 activity in purified, immunoprecipitated and recombinant or genetically modified HDAC-8 samples.
• Sample Type
  Purified, immunoprecipitated and recombinant or genetically modified HDAC3
• Features Benefits
  • Simple procedure; takes ~ 60 min • Fast and convenient • Kit contains the necessary reagents for accurate measurement of HDAC3 activity
• Storage Conditions
  -20°C
• Shipping Conditions
  gel pack
• Shelf life
  12 months
• Background
  Histone deacetylases (HDACs) represent a large family of enzymes identified as key regulators of nucleosomal histone acetylation, a major event that controls eukaryotic gene transcription and are classified into three groups. HDACs are transcriptional repressors with crucial roles in mammalian development. They are believed to be involved in important biological activities, such as cell differentiation, proliferation, apoptosis, and senescence. In BioVision’s HDAC-3 activity Kit, HDAC-3 and Developer will deacetylate and cleave the substrate [R-H-K-K(Ac)-AFC] to release the quenched fluorescent group (AFC), which can be detected at Em/Ex = 380/500 nm. The kit provides a rapid, simple, sensitive, and reliable test, which is also suitable for high throughput measurement of HDAC-3 activity in purified, immunoprecipitated and recombinant or genetically modified HDAC3 samples.
• Data Sheet Link
• Test
  Biovision supplies other types of Assays as 1.

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• Gene target
  HDAC3   Activity   Fluorometric   Kit  
• Gene symbol
  HDAC3
• Short name
  HDAC3 Activity Fluorometric Assay Kit
• Technique
  Assay, assays
• Host
  Assay
• Alternative name
  histone deacetylase 3 Activity fluorescence test reagent
• Alternative technique
  arrays, kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

Gene info

• Identity
  HGNC:4854
• Gene
  HDAC3
• Long gene name
  histone deacetylase 3
• Synonyms
  • RPD3
  • HD3
  • RPD3-2
  • KDAC3
• GenBank acession
  • AF059650
• Locus
  5q31.3
• Discovery year
  1999-01-29
• Entrez gene record
  8841
• Pubmed identfication
  • 9501169
  • 9464271
• RefSeq identity
  • NM_003883
• Classification
  • NCoR/SMRT transcriptional repression complex subunits
  • Histone deacetylases, class I
• VEGA ID
  OTTHUMG00000129629

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