HDAC Substrate, Fluorogenic

Alternative_name

Ac- Lys(Ac)-AMC
Description

A useful fluorometric substrate for histone deacetylases (HDACs). Ex(max): 330nm; Em(max): 395nm.
Structure Available

Yes
Peptide sequence

Ac- Lys(Ac)-AMC
Salt Form

No
Molecular Formula

C₂₀H₂₅N₃O₅
Molecular Weight

387.43
Cell Permeable

No
Purity

≥98% by HPLC
Solubilities

DMSO
Handling

Protect from light and air
Tag Line

A fluorogenic HDAC substrate
Storage Condition

-20 ̊C
Shipping Condition

gel pack
Shelf Life

36 months
SMILES

O=C(C)N[C@H](C(NC1=CC2=C(C(C)=CC(O2)=O)C=C1)=O)CCCCNC(C)=O
InChi

InChI=1S/C20H25N3O5/c1-12-10-19(26)28-18-11-15(7-8-16(12)18)23-20(27)17(22-14(3)25)6-4-5-9-21-13(2)24/h7-8,10-11,17H,4-6,9H2,1-3H3,(H,21,24)(H,22,25)(H,23,27)/t17-/m0/s1
InChi Key

TTZZVMJPVWHHEJ-KRWDZBQOSA-N
Data Sheet Link
MSDS Available

Yes

Identity

HGNC:14063
Gene

HDAC4
Long gene name

histone deacetylase 4
Synonyms gene
- BDMR
Synonyms gene name
- brachydactyly-mental retardation syndrome
Synonyms
- KIAA0288
- HDAC-A
- HDACA
- HD4
- HA6116
- HDAC-4
GenBank acession
- AB006626
Locus

2q37.3
Discovery year

2000-11-28
Entrez gene record

9759
Pubmed identfication
RefSeq identity
- NM_006037
Classification
- Histone deacetylases, class IIA
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000133344