Proteasome Substrate II, Fluorogenic

  • Catalog number
    B2059-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    Ac-RLR-AMC; Acetyl-Arg-Leu-Arg-7-amido-4-methylcoumarin; Proteasome Substrate
  • Description
    Proteasome Substrate II is a sensitive fluorogenic substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Excitation: 380 nm. Emission: 460 nm
  • CAS Number
    929903-87-7 (free base)
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₃₀H₄₆N₁₀O₆ .C₂HF₃O₂
  • Molecular Weight
    756.8
  • Cell Permeable
    Yes
  • Purity
    ≥97% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A sensitive fluorogenic proteasome substrate
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    131676392
  • SMILES
    CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C
  • InChi
    InChI=1S/C30H46N10O6/c1-16(2)13-23(40-27(44)21(37-18(4)41)7-5-11-35-29(31)32)28(45)39-22(8-6-12-36-30(33)34)26(43)38-19-9-10-20-17(3)14-25(42)46-24(20)15-19/h9-10,14-16,21-23H,5-8,11-13H2,1-4H3,(H,37,41)(H,38,43)(H,39,45)(H,40,44)(H4,31,32,35)(H4,33,34,36)/t21-,22-,23-/m0/s1
  • InChi Key
    DOIHRXFNOWSOMS-VABKMULXSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Proteasome Substrate II, Fluorogenic
  • Alternative name
    protein degradation aggregate Substrate II, Fluorogenic
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