Fluorogenic Proteasome Substrate Substrate

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Cas number

141223-71-4
Chemical s molecular weight

667.82
Chemical s main applications

Fluorogenic Proteasome Substrate (Z-VKM-AMC) is used to measure the peptidase activity of the 20S proteasome. Also used as a fluorogenic substrate for Alzheimer's Disease amyloid A4-generating enzymes. AMC has an excitation maximum of 340-360nm and an emission maximum of 440-460nm.
Other name

N-[(Phenylmethoxy)carbonyl]-L-valyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-methioninamide; 1: PN: WO2008077109 PAGE: 7 claimed sequence
Chemical s formula

C34H45N5O7S
Physical properties

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Boiling temperature

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Chemical s soluble in

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Chemical s specifications