Fulvestrant
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Catalog numberB1863-25
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PricePlease ask
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Size25 mg
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Alternative_name(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol; ICI182,780
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DescriptionFulvestrant is a high affinity estrogen receptor antagonist (IC₅₀ = 0.29 nM), that works by down-regulating and degrading the estrogen receptor, ERα. Reported to lack any partial agonist activity.
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CAS Number129453-61-8
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Structure AvailableYes
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Molecular FormulaC₂₃H₄₇F₅O₃S
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Molecular Weight606.77
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>50 mg/ml) or EtOH (>25 mg/ml)
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HandlingProtect from air and light
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Tag LineA high affinity estrogen receptor antagonist
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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MDL NumberMFCD00903953
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PubChem CID104741
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SMILESCC12CCC3C(C1CCC2O)C(CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F
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InChiInChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1
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InChi KeyVWUXBMIQPBEWFH-WCCTWKNTSA-N
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MSDS AvailableYes
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Gene target
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Short nameFulvestrant
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Alternative nameFulvestrant
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