Fulvestrant

  • Catalog number
    B1863-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol; ICI182,780
  • Description
    Fulvestrant is a high affinity estrogen receptor antagonist (IC₅₀ = 0.29 nM), that works by down-regulating and degrading the estrogen receptor, ERα. Reported to lack any partial agonist activity.
  • CAS Number
    129453-61-8
  • Structure Available
    Yes
  • Molecular Formula
    C₂₃H₄₇F₅O₃S
  • Molecular Weight
    606.77
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>50 mg/ml) or EtOH (>25 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A high affinity estrogen receptor antagonist
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00903953
  • PubChem CID
    104741
  • SMILES
    CC12CCC3C(C1CCC2O)C(CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F
  • InChi
    InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1
  • InChi Key
    VWUXBMIQPBEWFH-WCCTWKNTSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Fulvestrant
  • Alternative name
    Fulvestrant
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