Elastase Substrate, Fluorogenic

Alternative_name

MeOSuc - Ala - Ala - Pro - Val – AFC; MeOSuc-AAPV-AFC
Description

A useful fluorogenic substrate for neutrophil elastase. Cleavage of this peptide by the enzyme generates a strongly fluorescent AFC that is monitored fluorometrically. λex: 380 nm; λem: 500 nm.
Structure Available

Yes
Salt Form

No
Molecular Formula

C₃₁H₃₈N₅O₉F₃
Molecular Weight

681.67
Cell Permeable

No
Purity

≥99% by HPLC
Solubilities

DMSO
Handling

Protect from light and moisture
Tag Line

A fluorogenic substrate for neutrophil elastase
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

48 months
PubChem CID

4083261
PubChem CID Link
SMILES

CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(C(C)C)NC(=O)C3CCCN3C(=O)C(C)NC(=O)C(C) NC(=O)CCC(=O)OC
InChi

InChI=1S/C31H41N5O9/c1-16(2)27(30(42)34-20-9-10-21-17(3)14-26(39)45-23 (21)15-20)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11- 12-25(38)44-6/h9-10,14-16,18-19,22,27H,7-8,11-13H2,1-6H3,(H,32,37)(H,33, 40)(H,34,42)(H,35,41)
InChi Key

CMEUDEVBFFPSEI-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes