DPPIV Inhibitor, P32/98
-
Catalog number2571-5
-
Price156.08 USD
-
Size5 mg
-
-
Alternative_name(2S, 3S)-2-Amino-3 –methyl-1-(thiazolidin-3-yl)pentan-1-one hemi-fumarate
-
DescriptionCell-permeable. A potent, specific, and competitive transition-state substrate analog inhibitor of dipeptidyl peptidase IV (DPPIV) (Ki =130 nM). May be used in cell cuture (1-10 μM) or Experimental anti-diabetic agent. Has been used in vivo and cell culture.
-
CAS Number136259-20-6
-
Structure AvailableY
-
Salt FormNo
-
Molecular FormulaC₉H₁₈N₂OS · 1/2(C₄H₄O₄)
-
Molecular Weight260.36
-
Cell PermeableNo
-
Purity≥98% by TLC
-
HandlingProtect from air and moisture
-
Tag LineA potent Dipeptidylpeptidase IV (DPPIV) inhibitor
-
Storage Condition-20°C
-
Shipping ConditionGel pack
-
Shelf Life24 months
-
PubChem CID6918464
-
SMILESCCC(C)C(C(=O)N1CCSC1)N.C(=CC(=O)O)C(=O)O
-
InChiInChI=1S/C9H18N2OS.C4H4O4/c1-3-7(2)8(10)9(12)11-4-5-13-6-11;5-3(6)1-2-4(7)8/h7-8H,3-6,10H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t7-,8-;/m0./s1
-
InChi KeyZSOPWZQRZHWYFY-NUXPJIRBSA-N
-
MSDS AvailableYes
-
Additional descriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
-
Gene target
-
Gene symbolFAP, DPP4, C1QBP
-
Short nameDPPIV Inhibitor, P32/98
-
Alternative nameDPPIV suppressor, P32/98
-
Gene info
-
Identity
-
Gene
-
Long gene namefibroblast activation protein alpha
-
Synonyms gene name
- fibroblast activation protein, alpha
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1995-03-28
-
Entrez gene record
-
Pubmed identfication
-
Classification
- DASH family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namedipeptidyl peptidase 4
-
Synonyms gene
-
Synonyms gene name
- dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
- adenosine deaminase complexing protein 2
- dipeptidyl-peptidase 4
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1990-03-05
-
Entrez gene record
-
Pubmed identfication
-
Classification
- CD molecules
- DASH family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecomplement C1q binding protein
-
Synonyms gene
-
Synonyms gene name
- complement component 1, q subcomponent binding protein
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1995-12-11
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID