Chitotriosidase Activity Assay Kit (Fluorometric)

• Catalog number
  K512-100
• Price
  Please ask
• Size
  100 assays

• Summary
  • Detection method- Fluorescence (Ex/Em 320/445 nm) • Applications- Measurement of Chitotriosidase activity in various biological samples and purified/crude enzyme preparations
• Detection Method
  Fluorescence (Ex/Em 320/445 nm)
• Species Reactivity
  Mammalian
• Applications
  Measurement of Chitotriosidase activity in various biological samples and purified/crude enzyme preparations
• Sample Type
  • Adherent and suspension cell lysates • Animal tissues such as rat liver • Purified enzyme
• Features Benefits
  • Simple, rapid & convenient assay to measure Chitotriosidase activity • Includes Positive Control (Chitotriosidase)
• Storage Conditions
  -20°C
• Shipping Conditions
  gel pack
• Shelf life
  12 months
• Background
  Chitotriosidase (CHIT1 or chitinase-1), is a mammalian enzyme belonging to glycosyl hydrolase-18 family (EC 3.2.1.14), which can hydrolyze the β-(1, 4)-linkage between the adjacent N-acetyl glucosamine residues of chitin. CHIT1 is synthesized exclusively by activated macrophages both in normal and inflammatory conditions and, as a host defense factor, CHIT1 plays a pivotal role in infectious disease such as malaria and fungi infectious. Increased CHIT1 activity has also been found in patients suffering diseases such as bronchial asthma and atherosclerosis. CHIT1 has been used as a valuable diagnostic biomarker for monitoring the therapeutic efficacy of treatments for Gaucher’s disease or β-glucocerebrosidase deficiency. BioVision’s Chitotriosidase Activity Assay, utilizes a fluorogenic substrate that can be hydrolyzed by chitinase and a set of proprietary assay buffers that can distinguish specific CHIT1 activity from other hydrolases including Acidic Mammalian Chitinase. The kit provides a simple, specific, sensitive assay that can detect as low as 0.2 mU/ml of CHIT1 in a variety of biological samples.
• Data Sheet Link
• Test
  Biovision supplies other types of Assays as 1.

• Gene target
  Chitotriosidase   Activity   Kit   Fluorometric  
• Short name
  Chitotriosidase Activity Assay Kit (Fluorometric)
• Technique
  Assay, assays
• Host
  Assay
• Alternative name
  Chitotriosidase Activity test reagent (fluorescence)
• Alternative technique
  arrays, kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

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