Cathepsin Substrate, Fluorogenic

Alternative_name

Ac-LR-AFC; Ac-Leu-Arg-AFC; Acetyl-Leu-Arg-7-amido-4(trifluoromethyl)-coumarin
Description

A sensitive fluorogenic substrate for Cathepsin K. This substrate is also cleaved by cathepsin B, F, L, L2/V, S as well as by malaria parasite cysteine proteases falcipain-1, -2, -3, berghepain, and vivapain-2, -3
Structure Available

Yes
Salt Form

No
Molecular Formula

C₂₄H₃₁F₃N₆O₅
Molecular Weight

540.54
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

DMSO
Handling

Protect from air and light
Tag Line

A sensitive fluorogenic Cathepsin K substrate
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
SMILES

N/A
InChi

N/A
InChi Key

N/A
Data Sheet Link
MSDS Available

Yes
Gene

CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.