Apolipoprotein AI, Human Plasma

• Catalog number
  P1521-100
• Price
  Please ask
• Size
  100 µg

• Synonyms
  Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, Apolipoprotein A-I(1-242)
• Alternative_names
  Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, Apolipoprotein A-I(1-242)
• Description
  A protein promoting cholesterol efflux from tissues to the liver
• Recombinant
  False
• Source
  Human Plasma
• Purity by SDS PAGE
  >95%
• Assay
  SDS-PAGE
• Molecular Weight
  28000
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Appearance
  Sterile Filtered colorless solution
• Physical form description
  Liquid
• Background Information
  ApoA-I is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the “good cholesterol.” The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic Vascular diseases. Recombinant human ApoA-I is a 28.2 kDa protein of 244 amino acid residues.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Apolipoprotein   Plasma  
• Short name
  Apolipoprotein AI, Plasma
• Species
  Human, Humans
• Alternative name
  Apolipoprotein AI, H. sapiens Plasma

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