Mouse anti-human-MMP-13 (procollagenase 3), monoclonal, clone M66

• Catalog number
  31 105 304
• Price
  Please ask
• Size
  100 µg/ 100 µl

• Antibody category
  Monoclonal Antibody
• Antibody s description
  Protein G-purified monoclonal mouse anti-human procollagenase-3 IgG1, clone M66.The monoclonal antibody was raised against recombinant human procollagenase-3 expressed in insect cells. The IgG1 Fraction was purified by affinity chromatography.
• Raised in
  Mouse
• Research area of interest
  Diseases associated with MMP13 include Spondyloepimetaphyseal Dysplasia, Missouri Type and Metaphyseal Dysplasia, Spahr Type. Among its related pathways are Integrin Pathway and Development_Glucocorticoid receptor signaling.
• Package form
  liquid
• Clonality
  Monoclonal
• Antigen
  Recombinant human procollagenase-3 expressed in insect cells
• Reacts with
  Human
• Immunogen
  See the data sheet or contact us
• Contents
  20 mM Na-phosphate, pH 7.5, 150 mM NaCl, 0.01 NaN3
• Purity
  >95%
• Tested applications
  • ELISA, suggested dilution 1 : 2000 • Immunohistochemistry (parafin section), suggested dilution 1 : 2000, without proteolytic pre-treatment of embedded tissue
• Other names
  Protein G-purified monoclonal mouse anti-human procollagenase-3 IgG1, clone M66.The monoclonal antibody was raised against recombinant human procollagenase-3 expressed in insect cells. The IgG1 Fraction was purified by affinity chromatography.
• Crossreactivity
  no crossreactivty
• Antibody specificity
  reacts with human procollagenase-3. The antibody does not cross react with MMP13 cat. domain, MT1-MMP latent form (MMP-14), MT2-MMP cat. domain (MMP-15), MT3-MMP cat. domain (MMP-16), MT4-MMP cat. domain (MMP-17), MT5-MMP cat. domain (MMP-18), Gelatinase A (MMP-2) latent form, Gelatinase B (MMP-9) latent form, Collagenase 2 (MMP-8) latent form.
• Purification
  Protein G purified
• PubMed citations
  See the data sheet
• UniProt number
  P45452
• Storage conditions
  - 70°C
• Technical datasheet
  Contact us to receive the datasheet
• Representative figure
• Shipping condition
  dry ice
• Warnings
  For Research Use only.
• Other products
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  biotez supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Latin name
  Mus musculus

• Gene target
  MMP-13   procollagenase   monoclonal   M66  
• Gene symbol
  MMP13, MMP24, MMP14, PIRC58, MMP28, SNORD115-13, SNORD114-13, IGHV3OR16-13, IGLV3-13, MMP17
• Short name
  Mouse anti- -MMP-13 (procollagenase 3), monoclonal, clone M66
• Technique
  anti-Human, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, Monoclonals or monoclonal antibodies, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  not available conjugated
• Species
  Human, Humans, Mouses
• Alternative name
  Mouse Antibody tohuman-MMP-13 (procollagenase 3), monoclonal, clonality M66
• Alternative technique
  murine, antibodies
• Clone name
  M66

Gene info

• Identity
  HGNC:7159
• Gene
  MMP13
• Long gene name
  matrix metallopeptidase 13
• Synonyms gene name
  • matrix metalloproteinase 13 (collagenase 3)
• Synonyms
  • CLG3
• Synonyms name
  • collagenase 3
• GenBank acession
  • X75308
• Locus
  11q22.2
• Discovery year
  1994-11-20
• Entrez gene record
  4322
• Pubmed identfication
  • 8207000
• RefSeq identity
  • NM_002427
• Classification
  • M10 matrix metallopeptidases
  • Receptor ligands
• VEGA ID
  OTTHUMG00000165850

Gene info

• Identity
  HGNC:7172
• Gene
  MMP24
• Long gene name
  matrix metallopeptidase 24
• Synonyms gene name
  • matrix metalloproteinase 24 (membrane-inserted)
  • matrix metallopeptidase 24 (membrane-inserted)
• Synonyms
  • MT5-MMP
• Synonyms name
  • membrane-type 5 matrix metalloproteinase
• GenBank acession
  • AF131284
• Locus
  20q11.22
• Discovery year
  1999-08-06
• Entrez gene record
  10893
• Pubmed identfication
  • 10363975
• RefSeq identity
  • NM_006690
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000032330

Gene info

• Identity
  HGNC:7160
• Gene
  MMP14
• Long gene name
  matrix metallopeptidase 14
• Synonyms gene name
  • matrix metalloproteinase 14 (membrane-inserted)
  • matrix metallopeptidase 14 (membrane-inserted)
• Synonyms
  • MT1-MMP
• Synonyms name
  • membrane type 1 metalloprotease
  • membrane type 1-matrix metalloproteinase
• Locus
  14q11.2
• Discovery year
  1994-11-20
• Entrez gene record
  4323
• Pubmed identfication
  • 8015608
• RefSeq identity
  • NM_004995
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000028704

Gene info

• Identity
  HGNC:37562
• Gene
  PIRC58
• Long gene name
  piwi-interacting RNA cluster 58
• Locus
  13
• Discovery year
  2009-11-05
• Entrez gene record
  100313918
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:14366
• Gene
  MMP28
• Long gene name
  matrix metallopeptidase 28
• Synonyms gene name
  • matrix metalloproteinase 28
• Synonyms
  • MMP-25
  • MM28
  • EPILYSIN
  • MMP-28
• GenBank acession
  • AF315683
• Locus
  17q12
• Discovery year
  2001-01-09
• Entrez gene record
  79148
• Pubmed identfication
  • 11121398
  • 11255011
• RefSeq identity
  • NM_024302
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000188387

Gene info

• Identity
  HGNC:33032
• Gene
  SNORD115-13
• Long gene name
  small nucleolar RNA, C/D box 115-13
• Synonyms
  • HBII-52-13
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033450
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003305.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33001
• Gene
  SNORD114-13
• Long gene name
  small nucleolar RNA, C/D box 114-13
• Synonyms
  • 14q(II-13)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767591
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003206.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5637
• Gene
  IGHV3OR16-13
• Long gene name
  immunoglobulin heavy variable 3/OR16-13 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 3/OR16-13
• Synonyms
  • IGHV3/OR16-13
• GenBank acession
  • Z29610
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  100287372
• RefSeq identity
  • NG_011771
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000176357

Gene info

• Identity
  HGNC:5899
• Gene
  IGLV3-13
• Long gene name
  immunoglobulin lambda variable 3-13 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable 3-13
  • immunoglobulin lambda variable 3-13 pseudogene
• GenBank acession
  • X97463
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28801
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151215

Gene info

• Identity
  HGNC:7163
• Gene
  MMP17
• Long gene name
  matrix metallopeptidase 17
• Synonyms gene name
  • matrix metalloproteinase 17 (membrane-inserted)
  • matrix metallopeptidase 17 (membrane-inserted)
• Synonyms
  • MT4-MMP
• GenBank acession
  • X89576
• Locus
  12q24.33
• Discovery year
  1996-11-13
• Entrez gene record
  4326
• Pubmed identfication
  • 9878265
• RefSeq identity
  • NM_016155
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000168050

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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