PSAP Antibody

• Catalog number
  bs-2241R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PSAP Primary Polyclonal Antibody
• Also known as
  PSAP PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PSAP
• Specificity
  This is a highly specific antibody against PSAP.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSAP
• Gene ID number
  5660
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D, which are similar to each other and are sphingolipid hydrolase activator proteins. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in PSAP gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  A1 activator; Cerebroside sulfate activator; Co-beta-glucosidase; Component C; CSAct; Dispersin; GLBA; Glucosylceramidase activator; Proactivator polypeptide; Proactivator polypeptide precursor; Prosaposin sphingolipid activator protein 1; prosaposin variant Gaucher disease and variant metachromatic leukodystrophy; Protein A; Protein C; PSAP; SAP-1; SAP-2; SAP_HUMAN; SAP1; Saposin A; Saposin B; Saposin B Val; Saposin C; Saposin-D; Saposins; Sphingolipid activator protein 1; Sphingolipid activator protein 2; Sulfated glycoprotein 1; Sulfatide/GM1 activator.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PSAP  
• Gene symbol
  PSAP, MTCH1
• Short name
  Anti-PSAP
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PSAP Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9498
• Gene
  PSAP
• Long gene name
  prosaposin
• Synonyms gene
  • SAP1
  • GLBA
  • SAP2
• Synonyms gene name
  • sphingolipid activator protein-1
  • sphingolipid activator protein-2
• Synonyms name
  • variant Gaucher disease and variant metachromatic leukodystrophy
  • saposin-A
  • saposin-B
  • saposin-C
  • saposin-D
• GenBank acession
  • BC004275
• Locus
  10q22.1
• Discovery year
  1986-01-01
• Entrez gene record
  5660
• Pubmed identfication
  • 2717620
• RefSeq identity
  • NM_002778
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000018429

Gene info

• Identity
  HGNC:17586
• Gene
  MTCH1
• Long gene name
  mitochondrial carrier 1
• Synonyms gene name
  • mitochondrial carrier homolog 1 (C. elegans)
• Synonyms
  • CGI-64
  • PSAP
  • SLC25A49
• Synonyms name
  • solute carrier family 25, member 49
• GenBank acession
  • AF151822
• Locus
  6p21.2
• Discovery year
  2003-05-20
• Entrez gene record
  23787
• Pubmed identfication
  • 12377771
• RefSeq identity
  • NM_014341
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000014614

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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