anti- PSAP antibody

• Catalog number
  FNab06840
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
• Immunogen
  prosaposin
• Synonyms
  GLBA, SAP1
• Calculated MW
  62 kDa
• Uniprot ID
  P07602
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, IHC, WB, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human liver cancer using FNab06840(PSAP antibody) at dilution of 1:50
• Image4
  HepG2 cells were subjected to SDS PAGE followed by western blot with FNab06840( PSAP Antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PSAP  
• Gene symbol
  PSAP, MTCH1
• Short name
  anti- PSAP antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- PSAP (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9498
• Gene
  PSAP
• Long gene name
  prosaposin
• Synonyms gene
  • SAP1
  • GLBA
  • SAP2
• Synonyms gene name
  • sphingolipid activator protein-1
  • sphingolipid activator protein-2
• Synonyms name
  • variant Gaucher disease and variant metachromatic leukodystrophy
  • saposin-A
  • saposin-B
  • saposin-C
  • saposin-D
• GenBank acession
  • BC004275
• Locus
  10q22.1
• Discovery year
  1986-01-01
• Entrez gene record
  5660
• Pubmed identfication
  • 2717620
• RefSeq identity
  • NM_002778
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000018429

Gene info

• Identity
  HGNC:17586
• Gene
  MTCH1
• Long gene name
  mitochondrial carrier 1
• Synonyms gene name
  • mitochondrial carrier homolog 1 (C. elegans)
• Synonyms
  • CGI-64
  • PSAP
  • SLC25A49
• Synonyms name
  • solute carrier family 25, member 49
• GenBank acession
  • AF151822
• Locus
  6p21.2
• Discovery year
  2003-05-20
• Entrez gene record
  23787
• Pubmed identfication
  • 12377771
• RefSeq identity
  • NM_014341
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000014614

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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