LIMK1(Thr508)/LIMK2(Thr505) Antibody, Cy5.5 Conjugated
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Catalog numberbs-3247R-Cy5.5
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Price:
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Size0.1ml
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Long nameLIMK1(Thr508)/LIMK2(Thr505) Antibody, Cy5.5 Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationCy5.5
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenLIMK1 Thr508/LIMK2 Thr505
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SpecificityThis is a highly specific antibody against LIMK1 Thr508/LIMK2 Thr505.
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ModificationPhosphorylation
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Modification siteThr505
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505
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Gene ID number3984
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundLIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development; it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission675nm/694nm
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SynonymsLIMK1Thr508; EC 2.7.11.1; LIM domain kinase 1; LIM mot-containing protein kinase; LIMK; LIMK-1; LIMK2; LIMK-2; LIM domain kinase 2; LIMK1_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
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Additional conjugationCy5.5, Cy5.5
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ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
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French translationanticorps
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Gene target
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Gene symbolLIMK2, LIMK1
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Short nameAnti-LIMK1 Thr508/LIMK2 Thr505
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelCy5.5
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Alternative nameAnti-LIMK1 Thr508/LIMK2 Thr505 PAb Cy5.5
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameLIM domain kinase 2
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GenBank acession
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Locus
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Discovery year1997-08-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
- LIMK/TESK kinase family
- LIM domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameLIM domain kinase 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-03-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- LIM domain containing
- PDZ domain containing
- LIMK/TESK kinase family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data