LIMK1(Thr508)/LIMK2(Thr505) Antibody, Cy5 Conjugated

• Catalog number
  bs-3247R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  LIMK1(Thr508)/LIMK2(Thr505) Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  LIMK1 Thr508/LIMK2 Thr505
• Specificity
  This is a highly specific antibody against LIMK1 Thr508/LIMK2 Thr505.
• Modification
  Phosphorylation
• Modification site
  Thr505
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505
• Gene ID number
  3984
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development; it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  LIMK1Thr508; EC 2.7.11.1; LIM domain kinase 1; LIM mot-containing protein kinase; LIMK; LIMK-1; LIMK2; LIMK-2; LIM domain kinase 2; LIMK1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  LIMK1   Thr508   LIMK2   Thr505   Conjugated  
• Gene symbol
  LIMK2, LIMK1
• Short name
  Anti-LIMK1 Thr508/LIMK2 Thr505
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-LIMK1 Thr508/LIMK2 Thr505 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6614
• Gene
  LIMK2
• Long gene name
  LIM domain kinase 2
• GenBank acession
  • D45906
• Locus
  22q12.2
• Discovery year
  1997-08-28
• Entrez gene record
  3985
• Pubmed identfication
  • 8537403
  • 10591208
• RefSeq identity
  • NM_016733
• Classification
  • PDZ domain containing
  • LIMK/TESK kinase family
  • LIM domain containing
• VEGA ID
  OTTHUMG00000151251

Gene info

• Identity
  HGNC:6613
• Gene
  LIMK1
• Long gene name
  LIM domain kinase 1
• Synonyms
  • LIMK
• GenBank acession
  • D26309
• Locus
  7q11.23
• Discovery year
  1996-03-14
• Entrez gene record
  3984
• Pubmed identfication
  • 8673124
  • 8812460
• RefSeq identity
  • NM_002314
• Classification
  • LIM domain containing
  • PDZ domain containing
  • LIMK/TESK kinase family
• VEGA ID
  OTTHUMG00000023448

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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