LIMK1(Thr508)/LIMK2(Thr505) Antibody, Biotin Conjugated
-
Catalog number
bs-3247R-Biotin
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
LIMK1(Thr508)/LIMK2(Thr505) Antibody, Biotin Conjugated
-
Category
Conjugated Primary Antibodies
-
Conjugation
Biotin
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
LIMK1 Thr508/LIMK2 Thr505
-
Specificity
This is a highly specific antibody against LIMK1 Thr508/LIMK2 Thr505.
-
Modification
Phosphorylation
-
Modification site
Thr505
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
KLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505
-
Gene ID number
3984
-
Tested applications
WB, IHC-P
-
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500)
-
Crossreactivity
Human, Mouse, Rat
-
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen background
LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development; it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation Emission
N/A
-
Synonyms
LIMK1Thr508; EC 2.7.11.1; LIM domain kinase 1; LIM mot-containing protein kinase; LIMK; LIMK-1; LIMK2; LIMK-2; LIM domain kinase 2; LIMK1_HUMAN.
-
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
-
Additional conjugation
Biotinylated
-
French translation
anticorps
-
Gene target
-
Gene symbol
LIMK2, LIMK1
-
Short name
Anti-LIMK1 Thr508/LIMK2 Thr505
-
Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
-
Isotype
Immunoglobulin G (IgG)
-
Label
Biotin
-
Alternative name
Anti-LIMK1 Thr508/LIMK2 Thr505 PAb Biotin
-
Alternative technique
antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene name
LIM domain kinase 2
-
GenBank acession
-
Locus
-
Discovery year
1997-08-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- PDZ domain containing
- LIMK/TESK kinase family
- LIM domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
LIM domain kinase 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1996-03-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- LIM domain containing
- PDZ domain containing
- LIMK/TESK kinase family
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
