TCR alpha Antibody, ALEXA FLUOR 647

  • Catalog number
    bs-12328R-A647
  • Price
    Please ask
  • Size
    100ul
  • Long name
    TCR alpha Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
  • Also known as
    Anti-TCR alpha PAb ALEXA FLUOR 647
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 647
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    TCR alpha
  • Specificity
    This is a highly specific antibody against TCR alpha.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Subcellular location
    Extracellular
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TCR alpha
  • Gene ID Number
    171558
  • Tested applications
    FCM, IF(IHC-P)
  • Recommended dilutions
    FCM(1:20-100), IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Maturation of cytotoxic T lymphocytes is mediated in part by a structure on the T cell surface known as the T cell antigen receptor (TCR) complex. The pre-TCR complex consists of pre-TCR α, pre-TCR βand CD3, which together help coordinate early thymocyte development. Pre-TCR α chain is a type I transmembrane glycoprotein with an extracellular region similar to the constant domain of the immunoglobulin supergene family. Notch3 transgenic mice lacking pre-TCR α inhibits tumor development. In humans, acute lymphoblastic leukemias (ALL) in remission have lower transcript levels of Notch3, HES-1 and pre-TCR α transcripts a and b relative to proliferating ALLs. The human pre-TCR α gene is expressed in immature T cells and maps to chromosome 6p21.3.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    650nm/665nm
  • Synonyms
    T cell antigen receptor alpha polypeptide; T cell receptor alpha; T cell receptor alpha locus; TCRA; TCRD; TRA; PTCRA_HUMAN.
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-TCR alpha exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 647
  • Description
    The Anti-TCR alpha is a α- or alpha protein sometimes glycoprotein present in blood.
  • French translation
    anticorps
  • Gene target
    TCR   alpha  
  • Short name
    Anti-TCR alpha
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 647
  • Alternative name
    TCR alpha Polyclonal Antibody, ALEXA FLUOR 647
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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