- Catalog numberbs-12328R-A594
- Product nameTCR alpha Antibody, ALEXA FLUOR 594
- Size100ul
- PriceAsk For Price
- Short nameAnti-TCR alpha
- Long nameTCR alpha Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
- Also known asAnti-TCR alpha PAb ALEXA FLUOR 594
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 594
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenTCR alpha
- SpecificityThis is a highly specific antibody against TCR alpha.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Subcellular locationExtracellular
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TCR alpha
- Gene ID Number171558
- Tested applicationsFCM, IF(IHC-P)
- Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenMaturation of cytotoxic T lymphocytes is mediated in part by a structure on the T cell surface known as the T cell antigen receptor (TCR) complex. The pre-TCR complex consists of pre-TCR α, pre-TCR βand CD3, which together help coordinate early thymocyte development. Pre-TCR α chain is a type I transmembrane glycoprotein with an extracellular region similar to the constant domain of the immunoglobulin supergene family. Notch3 transgenic mice lacking pre-TCR α inhibits tumor development. In humans, acute lymphoblastic leukemias (ALL) in remission have lower transcript levels of Notch3, HES-1 and pre-TCR α transcripts a and b relative to proliferating ALLs. The human pre-TCR α gene is expressed in immature T cells and maps to chromosome 6p21.3.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission590nm/617nm
- SynonymsT cell antigen receptor alpha polypeptide; T cell receptor alpha; T cell receptor alpha locus; TCRA; TCRD; TRA; PTCRA_HUMAN.
- Gene targetTCR alpha
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 594
- label filter
- ALEXA FLUOR 594
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies