Alpha Glucosidase Antibody, ALEXA FLUOR 647

• Catalog number
  bs-13254R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  Alpha Glucosidase Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-GAA PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GAA
• Specificity
  This is a highly specific antibody against GAA.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GAA/Glucosidase alpha
• Gene ID Number
  2548
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  70 kDa lysosomal alpha-glucosidase; Acid alpha glucosidase; Acid maltase; Aglucosidase alfa; Alpha glucosidase; GAA; Glucosidase alpha acid Pompe disease glycogen storage disease type II; Glucosidase alpha acid; Glucosidase alpha; LYAG; LYAG_HUMAN; Lysosomal alpha glucosidase.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-GAA exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• Description
  The Anti-GAA is a α- or alpha protein sometimes glycoprotein present in blood.
• French translation
  anticorps

• Gene target
  Alpha   Glucosidase  
• Gene symbol
  SI, GANAB, GAA
• Short name
  Anti-GAA
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  Alpha Glucosidase Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10856
• Gene
  SI
• Long gene name
  sucrase-isomaltase
• Synonyms gene name
  • sucrase-isomaltase (alpha-glucosidase)
• Synonyms name
  • Oligosaccharide alpha-1,6-glucosidase
  • Oligo-1,6-glucosidase
  • alpha-glucosidase
  • Alpha-methylglucosidase
• GenBank acession
  • X63597
• Locus
  3q26.1
• Discovery year
  1986-01-01
• Entrez gene record
  6476
• Pubmed identfication
  • 2962903
  • 1353958
• RefSeq identity
  • NM_001041
• Classification
  • Glycoside hydrolase family 31
• VEGA ID
  OTTHUMG00000158065

Gene info

• Identity
  HGNC:4138
• Gene
  GANAB
• Long gene name
  glucosidase II alpha subunit
• Synonyms gene name
  • glucosidase, alpha; neutral AB
• Synonyms
  • GluII
  • G2AN
  • KIAA0088
  • GIIA
• Synonyms name
  • neutral alpha-glucosidase AB
• GenBank acession
  • AF144074
• Locus
  11q12.3
• Discovery year
  2001-06-22
• Entrez gene record
  23193
• Pubmed identfication
  • 6342981
  • 3881423
  • 10764838
• RefSeq identity
  • NM_198334
• Classification
  • Glycoside hydrolase family 31
• VEGA ID
  OTTHUMG00000167696

Gene info

• Identity
  HGNC:4065
• Gene
  GAA
• Long gene name
  alpha glucosidase
• Synonyms gene name
  • glucosidase, alpha; acid
  • glucosidase alpha, acid
• Synonyms name
  • Pompe disease
  • glycogen storage disease type II
• Locus
  17q25.3
• Discovery year
  1986-01-01
• Entrez gene record
  2548
• Classification
  • Glycoside hydrolase family 31
• VEGA ID
  OTTHUMG00000177537
• Locus Specific Databases
  • GAA - Pompe disease (glycogen storage disease type II)
  • Global Variome shared LOVD
  • LRG_673

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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