DNA Polymerase Kappa/POLK Antibody, ALEXA FLUOR 647

• Catalog number
  bs-13019R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  DNA Polymerase Kappa/POLK Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-DNA Polymerase Kappa/POLK PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DNA Polymerase Kappa/POLK
• Specificity
  This is a highly specific antibody against DNA Polymerase Kappa/POLK.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK
• Gene ID Number
  51426
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  DNA polymerase lambda (pol Kappa), also designated DNA polymerase Kappa or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol Kappa is a member of the DNA polymerase type-X family. Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol Kappa may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  DNA polymerase kappa; DINB protein; Short=DINP; POLK_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-DNA Polymerase Kappa/POLK exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  DNA   Polymerase   Kappa/POLK  
• Gene symbol
  POLK, PRKDC, HLA-DOA, TENT4A
• Short name
  Anti-DNA Polymerase Kappa/POLK
• Technique
  Antibody, dna, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  DNA Polymerase Kappa/POLK Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9183
• Gene
  POLK
• Long gene name
  DNA polymerase kappa
• Synonyms gene
  • DINB1
• Synonyms gene name
  • polymerase (DNA directed) kappa
  • polymerase (DNA) kappa
• Synonyms
  • POLQ
  • DINP
• Synonyms name
  • DINB protein
  • DNA polymerase kappa
• GenBank acession
  • AB027564
• Locus
  5q13.3
• Discovery year
  2000-08-11
• Entrez gene record
  51426
• Pubmed identfication
  • 10887153
  • 10518552
• RefSeq identity
  • NM_016218
• Classification
  • DNA polymerases
• VEGA ID
  OTTHUMG00000102107

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:16705
• Gene
  TENT4A
• Long gene name
  terminal nucleotidyltransferase 4A
• Synonyms gene
  • POLS
  • PAPD7
• Synonyms gene name
  • polymerase (DNA directed) sigma
  • PAP associated domain containing 7
  • poly(A) RNA polymerase D7, non-canonical
• Synonyms
  • POLK
  • TRF4
  • LAK-1
  • TRF4-1
• Synonyms name
  • topoisomerase-related function protein 4-1
  • polymerase (DNA-directed) sigma
  • DNA polymerase kappa
  • TUTase5
• GenBank acession
  • AF089896
• Locus
  5p15.31
• Discovery year
  2001-09-27
• Entrez gene record
  11044
• Pubmed identfication
  • 10066793
  • 10926539
  • 23376078
• RefSeq identity
  • NM_006999
• Classification
  • Terminal nucleotidyltransferases
  • Non-canonical poly(A) polymerases
• VEGA ID
  OTTHUMG00000090457

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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