Recombinant CASP8 And FADD Like Apoptosis Regulator (CFLAR)

• Catalog number
  RPU54215-50ug
• Price
  Please ask
• Size
  50ug

• Estimated Turnaround Time
  6-11 business days
• Gene Name
  NA
• Alternative Names
  CASH; CASP8AP1; CLARP; Casper; FLAME1; FLIP; I-FLICE; MRIT; USURPIN; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; Caspase-eight-related protein; FADD-like antiapoptotic molecule 1
• Source
  E.coli
• Purity
  ≥ 98%
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Shipping Conditions
  Ice packs
• Storage conditions
  Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
• Shelf life
  1 year
• Restriction
  For research use only. Not for diagnostic procedures.
• Description
  This 1 is suited for programmed cell-death studies.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CASP8   FADD   Like   Regulator   CFLAR  
• Gene symbol
  CFLAR-AS1, FADD, CASP8, CFLAR
• Short name
  Recombinant CASP8 FADD Like Apoptosis Regulator (CFLAR)
• Technique
  Recombinant, apoptosis, apoptosis pathway, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Rattus norvegicus (Rat)
• Alternative name
  Rec. caspase 8, apoptosis-related cysteine peptidase And Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain Like programmed cellular destruction Regulator (CASP8 and Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-like apoptosis regulator)
• Alternative technique
  rec, celldeath
• Alternative to gene target
  Fas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720

Gene info

• Identity
  HGNC:14437
• Gene
  CFLAR-AS1
• Long gene name
  CFLAR antisense RNA 1
• Synonyms gene
  • ALS2CR10
• Synonyms gene name
  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 10
  • CFLAR antisense RNA 1 (non-protein coding)
• GenBank acession
  • AB053312
• Locus
  2q33.1
• Discovery year
  2001-01-26
• Entrez gene record
  65072
• Pubmed identfication
  • 27855375
• RefSeq identity
  • NR_040030
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000154713

Gene info

• Identity
  HGNC:3573
• Gene
  FADD
• Long gene name
  Fas associated via death domain
• Synonyms gene name
  • Fas (TNFRSF6)-associated via death domain
• Synonyms
  • MORT1
  • GIG3
• Synonyms name
  • Fas-associating protein with death domain
  • Fas-associating death domain-containing protein
  • mediator of receptor-induced toxicity
  • growth-inhibiting gene 3 protein
• GenBank acession
  • U24231
• Locus
  11q13.3
• Discovery year
  1999-05-07
• Entrez gene record
  8772
• Pubmed identfication
  • 7536190
  • 7538907
• RefSeq identity
  • NM_003824
• Classification
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000167264
• Locus Specific Databases
  • LRG_228

Gene info

• Identity
  HGNC:1509
• Gene
  CASP8
• Long gene name
  caspase 8
• Synonyms gene name
  • caspase 8, apoptosis-related cysteine protease
  • caspase 8, apoptosis-related cysteine peptidase
• Synonyms
  • MCH5
  • MACH
  • FLICE
  • Casp-8
• GenBank acession
  • U60520
• Locus
  2q33.1
• Discovery year
  1996-11-11
• Entrez gene record
  841
• Pubmed identfication
  • 8681376
  • 8681377
• RefSeq identity
  • NM_001228
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132821
• Locus Specific Databases
  • CASP8base: Mutation registry for Caspase 8 deficiency
  • LRG_34

Gene info

• Identity
  HGNC:1876
• Gene
  CFLAR
• Long gene name
  CASP8 and FADD like apoptosis regulator
• Synonyms gene
  • CASP8AP1
• Synonyms gene name
  • CASP8 and FADD-like apoptosis regulator
• Synonyms
  • CASH
  • Casper
  • CLARP
  • FLAME
  • FLIP
  • I-FLICE
  • MRIT
  • c-FLIP
  • cFLIP
• GenBank acession
  • AF005774
• Locus
  2q33.1
• Discovery year
  1999-05-07
• Entrez gene record
  8837
• Pubmed identfication
  • 9208847
  • 9217161
• RefSeq identity
  • NM_003879
• Classification
  • Receptor ligands
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132819

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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