FITC-linked Antibody to CASP8 And FADD Like Apoptosis Regulator (CFLAR)

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• Catalog number
  MBS2017525
• Price:

  634.89 USD

  Ask for price
• Size
  0,1 mg

# #

• Other size
  please contact us to order other different size
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This MyBioSource Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MyBioSource FITC is highly sensitive to pH extremes.
• Description
  This 1 is suited for programmed cell-death studies.
• Conjugation
  Anti-FITC Antibody
• French translation
  anticorps

#

• Gene target
  linked   CASP8   FADD   Like   Regulator   CFLAR  
• Gene symbol
  FADD, CFLAR-AS1, CASP8, CFLAR
• Short name
  FITC-linked Antibody CASP8 FADD Like Apoptosis Regulator (CFLAR)
• Technique
  apoptosis, Antibody, FITC, antibodies against human proteins, antibodies for, apoptosis pathway, Fluorescein
• Label
  FITC
• Alternative name
  fluorecein-linked (antibody to-) to caspase 8, apoptosis-related cysteine peptidase And Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain Like programmed cellular destruction Regulator (CASP8 and Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-like apoptosis regulator)
• Alternative technique
  celldeath, antibodies, fluorescine
• Alternative to gene target
  Fas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720

Gene info

• Identity
  HGNC:3573
• Gene
  FADD
• Long gene name
  Fas associated via death domain
• Synonyms gene name
  • Fas (TNFRSF6)-associated via death domain
• Synonyms
  • MORT1
  • GIG3
• Synonyms name
  • Fas-associating protein with death domain
  • Fas-associating death domain-containing protein
  • mediator of receptor-induced toxicity
  • growth-inhibiting gene 3 protein
• GenBank acession
  • U24231
• Locus
  11q13.3
• Discovery year
  1999-05-07
• Entrez gene record
  8772
• Pubmed identfication
  • 7536190
  • 7538907
• RefSeq identity
  • NM_003824
• Classification
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000167264
• Locus Specific Databases
  • LRG_228

Gene info

• Identity
  HGNC:14437
• Gene
  CFLAR-AS1
• Long gene name
  CFLAR antisense RNA 1
• Synonyms gene
  • ALS2CR10
• Synonyms gene name
  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 10
  • CFLAR antisense RNA 1 (non-protein coding)
• GenBank acession
  • AB053312
• Locus
  2q33.1
• Discovery year
  2001-01-26
• Entrez gene record
  65072
• Pubmed identfication
  • 27855375
• RefSeq identity
  • NR_040030
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000154713

Gene info

• Identity
  HGNC:1509
• Gene
  CASP8
• Long gene name
  caspase 8
• Synonyms gene name
  • caspase 8, apoptosis-related cysteine protease
  • caspase 8, apoptosis-related cysteine peptidase
• Synonyms
  • MCH5
  • MACH
  • FLICE
  • Casp-8
• GenBank acession
  • U60520
• Locus
  2q33.1
• Discovery year
  1996-11-11
• Entrez gene record
  841
• Pubmed identfication
  • 8681376
  • 8681377
• RefSeq identity
  • NM_001228
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132821
• Locus Specific Databases
  • CASP8base: Mutation registry for Caspase 8 deficiency
  • LRG_34

Gene info

• Identity
  HGNC:1876
• Gene
  CFLAR
• Long gene name
  CASP8 and FADD like apoptosis regulator
• Synonyms gene
  • CASP8AP1
• Synonyms gene name
  • CASP8 and FADD-like apoptosis regulator
• Synonyms
  • CASH
  • Casper
  • CLARP
  • FLAME
  • FLIP
  • I-FLICE
  • MRIT
  • c-FLIP
  • cFLIP
• GenBank acession
  • AF005774
• Locus
  2q33.1
• Discovery year
  1999-05-07
• Entrez gene record
  8837
• Pubmed identfication
  • 9208847
  • 9217161
• RefSeq identity
  • NM_003879
• Classification
  • Receptor ligands
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132819

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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