Biotin-Linked Antibody to CASP8 And FADD Like Apoptosis Regulator (CFLAR)

• Catalog number
  MBS2013603
• Price
  Please ask
• Size
  0,1 mg

• Other size
  please contact us to order other different size
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Description
  This 1 is suited for programmed cell-death studies.
• Conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  Linked   CASP8   FADD   Like   Regulator   CFLAR  
• Gene symbol
  FADD, CFLAR-AS1, CASP8, CFLAR
• Short name
  -Linked Antibody CASP8 FADD Like Apoptosis Regulator (CFLAR)
• Technique
  apoptosis, Antibody, antibodies against human proteins, antibodies for, apoptosis pathway
• Label
  Biotin
• Alternative name
  biotinilated-Linked (antibody to-) to caspase 8, apoptosis-related cysteine peptidase And Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain Like programmed cellular destruction Regulator (CASP8 and Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-like apoptosis regulator)
• Alternative technique
  celldeath, antibodies
• Alternative to gene target
  Fas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720

Gene info

• Identity
  HGNC:3573
• Gene
  FADD
• Long gene name
  Fas associated via death domain
• Synonyms gene name
  • Fas (TNFRSF6)-associated via death domain
• Synonyms
  • MORT1
  • GIG3
• Synonyms name
  • Fas-associating protein with death domain
  • Fas-associating death domain-containing protein
  • mediator of receptor-induced toxicity
  • growth-inhibiting gene 3 protein
• GenBank acession
  • U24231
• Locus
  11q13.3
• Discovery year
  1999-05-07
• Entrez gene record
  8772
• Pubmed identfication
  • 7536190
  • 7538907
• RefSeq identity
  • NM_003824
• Classification
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000167264
• Locus Specific Databases
  • LRG_228

Gene info

• Identity
  HGNC:14437
• Gene
  CFLAR-AS1
• Long gene name
  CFLAR antisense RNA 1
• Synonyms gene
  • ALS2CR10
• Synonyms gene name
  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 10
  • CFLAR antisense RNA 1 (non-protein coding)
• GenBank acession
  • AB053312
• Locus
  2q33.1
• Discovery year
  2001-01-26
• Entrez gene record
  65072
• Pubmed identfication
  • 27855375
• RefSeq identity
  • NR_040030
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000154713

Gene info

• Identity
  HGNC:1509
• Gene
  CASP8
• Long gene name
  caspase 8
• Synonyms gene name
  • caspase 8, apoptosis-related cysteine protease
  • caspase 8, apoptosis-related cysteine peptidase
• Synonyms
  • MCH5
  • MACH
  • FLICE
  • Casp-8
• GenBank acession
  • U60520
• Locus
  2q33.1
• Discovery year
  1996-11-11
• Entrez gene record
  841
• Pubmed identfication
  • 8681376
  • 8681377
• RefSeq identity
  • NM_001228
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132821
• Locus Specific Databases
  • CASP8base: Mutation registry for Caspase 8 deficiency
  • LRG_34

Gene info

• Identity
  HGNC:1876
• Gene
  CFLAR
• Long gene name
  CASP8 and FADD like apoptosis regulator
• Synonyms gene
  • CASP8AP1
• Synonyms gene name
  • CASP8 and FADD-like apoptosis regulator
• Synonyms
  • CASH
  • Casper
  • CLARP
  • FLAME
  • FLIP
  • I-FLICE
  • MRIT
  • c-FLIP
  • cFLIP
• GenBank acession
  • AF005774
• Locus
  2q33.1
• Discovery year
  1999-05-07
• Entrez gene record
  8837
• Pubmed identfication
  • 9208847
  • 9217161
• RefSeq identity
  • NM_003879
• Classification
  • Receptor ligands
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132819

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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