Tak-285, dual Inhibitor of Her2/EGFR Tyr kinase (IC50=17 nM; mol wt 547; >98%)
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Catalog number
SM-101130-25
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Price
Please ask
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Size
25 mg
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Stock availability
Available
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Category
Custom Service
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Antibody type
N/A
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Antibody host
N/A
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Antibody conjugate
N/A
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Technical datasheet
Contact Gentaur to request the datasheet or ask our specialists for more information.
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Notes
The Tak-285, dual Inhibitor of Her2/EGFR Tyr kinase (IC50=17 nM; mol wt 547; >98%) is manufactured for Research Use Only or for diagnostics purposes.
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Test
The duality of this product lies in it's dual specificity to the gene, pH or protein. Mainly in phosphorylation by specific phosphatases.
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Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbol
EGFR-AS1, EGILA, EGFR, RHBDF1
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Short name
Tak-285, Inhibitor of Her2/EGFR Tyr kinase (IC50=17 nM; mol wt 547; >98%)
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Label
dual
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Species
N/A
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Alternative name
Tak-285, dual suppressor on Her2/epidermal growth factor receptor L-tyrosine phosphorylation catalyst (IC50=17 nanometer; mol wt 547; >98%)
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Alternative to gene target
epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217
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Gene info
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Identity
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Gene
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Long gene name
EGFR antisense RNA 1
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Locus
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Discovery year
2012-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
EGFR interacting lncRNA
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Synonyms
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Locus
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Discovery year
2019-09-27
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Pubmed identfication
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Classification
- Long non-coding RNAs with non-systematic symbols
Gene info
Gene info
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Identity
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Gene
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Long gene name
rhomboid 5 homolog 1
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Synonyms gene
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Synonyms gene name
- chromosome 16 open reading frame 8
- rhomboid family 1 (Drosophila)
- rhomboid 5 homolog 1 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2003-04-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Product images
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