CD126 (IL 6 Receptor, neutralizing, IL-6R)
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Catalog number
GEN600862
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Price
Please ask
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Size
100ug
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Also known as
CD126
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Other names
N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
2Q1481
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes both the soluble and membrane bound human IL-6 receptor. B-R6 will inhibit IL-6 mediated proliferation of XG-1 cells and partially blocks the binding of IL-6 to its receptor. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Highly Purified by Ion Exchange chromatography.
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Form Appearance
Supplied as a liquid in PBS, 0.09% sodium azide.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.Â
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Tested applications
ELISA (EL/EIA), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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Test
To cause (an acid or base) to undergo neutralization.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
IL6R, IL6R-AS1, IL36G, IL25, IL22, IL18, IL37, IL17C, IL17A, IL17D
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Short name
CD126 (IL 6 Receptor, , IL-6R)
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Alternative name
Anti-CD126 (Interleukin 6 Receptor, neutralizing, IL-6R)
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Gene info
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Identity
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Gene
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Long gene name
interleukin 6 receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
IL6R antisense RNA 1
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Synonyms
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Locus
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Discovery year
2017-08-30
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Pubmed identfication
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Classification
Gene info
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Identity
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Gene
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Long gene name
interleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 25
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Synonyms gene
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-01-26
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 22
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
interleukin 18
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Synonyms gene name
- interleukin 18 (interferon-gamma-inducing factor)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1997-07-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 37
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 7 (zeta)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 17C
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-01-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 17A
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Synonyms gene
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Synonyms gene name
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1993-10-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
interleukin 17D
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2000-05-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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