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IL-1 RA murine recombinant

IL-1 RA murine recombinant is available 3 times from Biovision labs

4264-10 | IL-1 RA, murine recombinant size: 10 ug | 184.44 USD

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4264-50 | IL-1 RA, murine recombinant size: 50 ug | 394.67 USD

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4264-1000 | IL-1 RA, murine recombinant size: 1 mg | 4,417.39 USD

Catalog number 4264-1000
Supplier Biovision
Price 4,417.39 USD
Size 1 mg
1. Gene info
Identity 5990
Gene IL19
Long gene name interleukin 19
Synonyms
  • IL-19
  • MDA1
  • ZMDA1
  • IL-10C
  • NG.1
Synonyms name
  • melanoma differentiation associated protein-like protein
GenBank acession
  • AF192498
Locus 1q32.1
Discovery year 2000-03-29
Entrez gene record 29949
Pubmed identfication
  • 11196675
RefSeq identity
  • NM_153758
Classification
  • Interleukins
Havana BLAST/BLAT OTTHUMG00000036387
2. Gene info
Identity 5991
Gene IL1A
Long gene name interleukin 1 alpha
Synonyms gene
  • IL1
Synonyms
  • IL1F1
  • IL-1A
  • IL1-ALPHA
Synonyms name
  • preinterleukin 1 alpha
  • hematopoietin-1
  • pro-interleukin-1-alpha
GenBank acession
  • M28983
Locus 2q14.1
Discovery year 2001-06-22
Entrez gene record 3552
Pubmed identfication
  • 8188271
  • 2989698
RefSeq identity
  • NM_000575
Classification
  • Interleukins
Havana BLAST/BLAT OTTHUMG00000131315
Product images
    #0#.jpeg
Synonyms IRAP, IL1F3, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, F630041P17Rik,
Alternative_names IRAP, IL1F3, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, F630041P17Rik,
Description A natural inhibitor of the pro-inflammatory effect of IL1β
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥98%
Assay SDS-PAGE
Biological activity The mouse IL-1Ra is capable of inhibiting IL-1-alpha activity in helper T cell line D10.G4.1.
Molecular Weight 17.4 kDa
Storage Temp. -20°C
Shipping Blue ice
Shelf Life 12 months
Appearance Lyophilized protein
Physical form description Lyophilized from H₂O containing NaHCO₃
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile ddH₂O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers.
Background Information Interleukin-1 RA is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1-alpha (IL1A) and interleukin 1-beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. IL1 ra Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17.4kDa. The IL1RA is purified by proprietary chromatographic techniques.
Amino acid sequence The sequence of the first six N-terminal amino acids was determined and was found to be Ala-Cys-Arg-Pro-Ser-Gly.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Gene The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetIL-1 murine
Short name IL-1 RA, murine recombinant
Technique Recombinant
Alternative name Interleukin-1 RA, murine recombinant
Alternative technique rec
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  • murine
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