D-(+)-Biotin

Alternative_name

D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H
Description

D-(+)-Biotin is a coenzyme and a B vitamin. May be used to elute proteins from avidin/streptavidin resins.
CAS Number

58-85-5
Structure Available

Yes
Salt Form

No
Molecular Formula

C₁₀H₁₆N₂O₃S
Molecular Weight

244.31
Cell Permeable

No
Purity

≥98%
Solubilities

DMSO (>40 mg/ml)
Handling

Protect from air and light
Tag Line

A coenzyme and a B vitamin.
Storage Condition

+4°C
Shipping Condition

RT
Shelf Life

36 months
MDL Number

MFCD00005541
PubChem CID

171548
PubChem CID Link
SMILES

C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2
InChi

nChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
InChi Key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N
Data Sheet Link
MSDS Available

Yes
Properties

Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Conjugation

Biotinylated

Identity

HGNC:2771
Gene

CFD
Long gene name

complement factor D
Synonyms gene
- DF
- PFD
Synonyms gene name
- D component of complement (adipsin)
- properdin factor D
- complement factor D (adipsin)
Synonyms
- ADN
Synonyms name
- adipsin
GenBank acession
- M84526
Locus

19p13.3
Discovery year

1992-10-21
Entrez gene record

1675
Pubmed identfication
- 1374388
RefSeq identity
- NM_001928
Classification
- Granule associated serine proteases of immune defence
- Complement system activation components
VEGA ID

OTTHUMG00000181840
Locus Specific Databases
- CFDbase: Mutation registry for Factor D deficiency (previously known as DFbase)
- LRG_46