Goat Polyclonal to Human PTPN6 / SHP-1[PTPN6 / SHP-1]

Products_type

Antibody
Products_gene_name

[PTPN6]
Reactivity

Hamster, Human, Mouse, RatPredicted Reactivity: Gorilla, Monkey, Dog, Horse, Pig (at least 90% immunogen sequence identity)
Latin name

Capra aegagrus hircus
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group

Polyclonals and antibodies
About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Gene target

PTPN6 SHP-1[PTPN6 SHP-1]
Gene symbol

PTPN6, NR0B2, PTPN11, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1
Short name

Goat Polyclonal PTPN6 / SHP-1[PTPN6 / SHP-1]
Technique

Polyclonal, Goat, goats, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
Host

Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
Species

Human, Goats, Humans
Alternative name

caprine polyclonal to H. sapiens protein tyrosine phosphatase, non-receptor classification 6 / SHP-1[protein tyrosine phosphatase, non-receptor classification 6 / SHP-1]
Alternative technique

polyclonals, caprine
Alternative to gene target

protein tyrosine phosphatase, non-receptor type 6, HCP and HCPH and HPTP1C and PTP-1C and SH-PTP1 and SHP-1 and SHP-1L and SHP1, PTPN6 and IDBG-15719 and ENSG00000111679 and 5777, SH2 domain binding, nuclei, Ptpn6 and IDBG-187635 and ENSMUSG00000004266 and 15170, PTPN6 and IDBG-640141 and ENSBTAG00000020294 and 512312

Identity

HGNC:9658
Gene

PTPN6
Long gene name

protein tyrosine phosphatase non-receptor type 6
Synonyms
- HCP
- HCPH
- PTP-1C
- SHP-1
- SHP1
Locus

12p13.31
Discovery year

1992-02-12
Entrez gene record

5777
Pubmed identfication
- 1639416
RefSeq identity
- NM_002831
Classification
- Protein tyrosine phosphatases non-receptor type
- SH2 domain containing
VEGA ID

OTTHUMG00000168518

Identity

HGNC:9644
Gene

PTPN11
Long gene name

protein tyrosine phosphatase non-receptor type 11
Synonyms gene
- NS1
Synonyms gene name
- Noonan syndrome 1
- protein tyrosine phosphatase, non-receptor type 11
Synonyms
- BPTP3
- SH-PTP2
- SHP-2
- PTP2C
- SHP2
Synonyms name
- SH2 domain-containing protein tyrosine phosphatase 2
GenBank acession
- D13540
Locus

12q24.13
Discovery year

1993-03-03
Entrez gene record

5781
Pubmed identfication
- 7894486
- 1280823
Classification
- Protein tyrosine phosphatases non-receptor type
- SH2 domain containing
VEGA ID

OTTHUMG00000134334
Locus Specific Databases
- LRG_614

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081