Nuclear Receptor SHP (NR0B2)

• Catalog number
  GEN604269
• Price
  Please ask
• Size
  50ug

• Also known as
  Nuclear Receptor SHP
• Other names
  nuclear receptor subfamily 0 group B member 2; Nuclear receptor subfamily 0 group B member 2; nuclear receptor subfamily 0 group B member 2; nuclear receptor SHP; small heterodimer partner; orphan nuclear receptor SHP; nuclear receptor subfamily 0, group B, member 2; Orphan nuclear receptor SHP; Small heterodimer partner
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  NR0B2; NR0B2; SHP; SHP1; SHP
• Gene name synonims
  NR0B2; NR0B2; SHP; SHP1; SHP
• Other gene names
  NR0B2; NR0B2; SHP; SHP1; SHP
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a
• Clone
  6D624
• Host organism
  Rat (Rattus norvegicus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human SHP.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Purified
• Form Appearance
  Liquid. Purified IgG in PBS, pH 7.4. No preservative added.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Receptor   SHP   NR0B2  
• Gene symbol
  NR0B2, PTPN6, PTPN11
• Short name
  Receptor SHP (NR0B2)
• Alternative name
  Anti-Nuclear Receptor SHP (NR0B2)

Gene info

• Identity
  HGNC:7961
• Gene
  NR0B2
• Long gene name
  nuclear receptor subfamily 0 group B member 2
• Synonyms gene name
  • nuclear receptor subfamily 0, group B, member 2
• Synonyms
  • SHP
• GenBank acession
  • AF044316
• Locus
  1p36.11
• Discovery year
  1999-08-19
• Entrez gene record
  8431
• Pubmed identfication
  • 9603951
• Classification
  • Nuclear receptor subfamily 0 group B
• VEGA ID
  OTTHUMG00000004231

Gene info

• Identity
  HGNC:9658
• Gene
  PTPN6
• Long gene name
  protein tyrosine phosphatase non-receptor type 6
• Synonyms
  • HCP
  • HCPH
  • PTP-1C
  • SHP-1
  • SHP1
• Locus
  12p13.31
• Discovery year
  1992-02-12
• Entrez gene record
  5777
• Pubmed identfication
  • 1639416
• RefSeq identity
  • NM_002831
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000168518

Gene info

• Identity
  HGNC:9644
• Gene
  PTPN11
• Long gene name
  protein tyrosine phosphatase non-receptor type 11
• Synonyms gene
  • NS1
• Synonyms gene name
  • Noonan syndrome 1
  • protein tyrosine phosphatase, non-receptor type 11
• Synonyms
  • BPTP3
  • SH-PTP2
  • SHP-2
  • PTP2C
  • SHP2
• Synonyms name
  • SH2 domain-containing protein tyrosine phosphatase 2
• GenBank acession
  • D13540
• Locus
  12q24.13
• Discovery year
  1993-03-03
• Entrez gene record
  5781
• Pubmed identfication
  • 7894486
  • 1280823
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000134334
• Locus Specific Databases
  • LRG_614

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