Nuclear Receptor SHP (NR0B2)

• Catalog number
  MBS604269
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [Nuclear Receptor SHP]
• Products_name_syn
  [Anti -Nuclear Receptor SHP (NR0B2)]
• Other_names
  [nuclear receptor subfamily 0 group B member 2; Nuclear receptor subfamily 0 group B member 2; nuclear receptor subfamily 0 group B member 2; nuclear receptor SHP; small heterodimer partner; orphan nuclear receptor SHP; nuclear receptor subfamily 0, group B, member 2; Orphan nuclear receptor SHP; Small heterodimer partner]
• Other_gene_names
  [NR0B2; NR0B2; SHP; SHP1; SHP]
• Clonality
  Monoclonal
• Clone
  [6D624]
• Reactivity
  Human
• Specificity
  Recognizes human SHP.
• Purity
  Purified Purified
• Form
  Liquid. Purified IgG in PBS, pH 7.4. No preservative added.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Receptor   SHP   NR0B2  
• Gene symbol
  NR0B2, PTPN6, PTPN11
• Short name
  Receptor SHP (NR0B2)
• Host
  Rat
• Isotype
  IgG2a
• Alternative name
  Nuclear Receptor SHP (NR0B2)

Gene info

• Identity
  HGNC:7961
• Gene
  NR0B2
• Long gene name
  nuclear receptor subfamily 0 group B member 2
• Synonyms gene name
  • nuclear receptor subfamily 0, group B, member 2
• Synonyms
  • SHP
• GenBank acession
  • AF044316
• Locus
  1p36.11
• Discovery year
  1999-08-19
• Entrez gene record
  8431
• Pubmed identfication
  • 9603951
• Classification
  • Nuclear receptor subfamily 0 group B
• VEGA ID
  OTTHUMG00000004231

Gene info

• Identity
  HGNC:9658
• Gene
  PTPN6
• Long gene name
  protein tyrosine phosphatase non-receptor type 6
• Synonyms
  • HCP
  • HCPH
  • PTP-1C
  • SHP-1
  • SHP1
• Locus
  12p13.31
• Discovery year
  1992-02-12
• Entrez gene record
  5777
• Pubmed identfication
  • 1639416
• RefSeq identity
  • NM_002831
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000168518

Gene info

• Identity
  HGNC:9644
• Gene
  PTPN11
• Long gene name
  protein tyrosine phosphatase non-receptor type 11
• Synonyms gene
  • NS1
• Synonyms gene name
  • Noonan syndrome 1
  • protein tyrosine phosphatase, non-receptor type 11
• Synonyms
  • BPTP3
  • SH-PTP2
  • SHP-2
  • PTP2C
  • SHP2
• Synonyms name
  • SH2 domain-containing protein tyrosine phosphatase 2
• GenBank acession
  • D13540
• Locus
  12q24.13
• Discovery year
  1993-03-03
• Entrez gene record
  5781
• Pubmed identfication
  • 7894486
  • 1280823
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000134334
• Locus Specific Databases
  • LRG_614

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