Caspase Family Inhibitor, Q-VD-OPH, Negative Control

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Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Isotype or positive controls by peptides, antibodies and deactivated samples. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Negative control peptides or isotypes available of the different species.

Identity

HGNC:4390
Gene

GNAQ
Long gene name

G protein subunit alpha q
Synonyms gene name
- guanine nucleotide binding protein (G protein), q polypeptide
Synonyms
- G-ALPHA-q
- GAQ
Locus

9q21.2
Discovery year

1992-12-15
Entrez gene record

2776
Pubmed identfication
- 8825633
RefSeq identity
- NM_002072
Classification
- G protein subunits alpha, group q
VEGA ID

OTTHUMG00000020059
Locus Specific Databases
- LRG_1110

Identity

HGNC:4738
Gene

H2AC20
Long gene name

H2A clustered histone 20
Synonyms gene
- H2A
- H2AFQ
- HIST2H2AC
Synonyms gene name
- H2A histone family, member Q
- histone 2, H2ac
- histone cluster 2, H2ac
- histone cluster 2 H2A family member c
Synonyms
- H2A/q
GenBank acession
- AY131973
Locus

1q21.2
Discovery year

1998-08-27
Entrez gene record

8338
Pubmed identfication
- 1469070
- 9439656
- 12408966
RefSeq identity
- NM_003517
Classification
- H2A histones
VEGA ID

OTTHUMG00000035825

Identity

HGNC:16918
Gene

SYNCRIP
Long gene name

synaptotagmin binding cytoplasmic RNA interacting protein
Synonyms
- NSAP1
- GRY-RBP
- dJ3J17.2
- HNRPQ1
- hnRNP-Q
- HNRNPQ
Synonyms name
- heterogeneous nuclear ribonucleoprotein Q
GenBank acession
- AF037448
Locus

6q14.3
Discovery year

2003-11-27
Entrez gene record

10492
Pubmed identfication
- 9847309
- 11352648
RefSeq identity
- NM_006372
Classification
- RNA binding motif containing
- Heterogeneous nuclear ribonucleoproteins
VEGA ID

OTTHUMG00000015141

Identity

HGNC:4760
Gene

H2BC21
Long gene name

H2B clustered histone 21
Synonyms gene
- H2B
- H2BFQ
- HIST2H2BE
Synonyms gene name
- H2B histone family, member Q
- histone 2, H2be
- histone cluster 2, H2be
- histone cluster 2 H2B family member e
Synonyms
- H2B/q
- H2B.1
- H2BE
- H2B-GL105
GenBank acession
- AY131979
Locus

1q21.2
Discovery year

1998-08-27
Entrez gene record

8349
Pubmed identfication
RefSeq identity
- NM_003528
Classification
- H2B histones
VEGA ID

OTTHUMG00000012095

Name

Models, Chemical
Concept

Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
- E05.599.495