Caspase Family Inhibitor Set IV
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Catalog number
K220-12-25
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Price
Please ask
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Size
12x25 ul
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Description
A convenient set containing twelve ready-to-use capase family inhibitors. The set contains 25 µl (2 mM in DMSO) each of the following five inhibitors: Caspase-1 Inhibitor, Z-YVAD(OMe)-FMK; Caspase-2 Inhibitor, Z-VD(OMe)-VAD(OMe)-FMK; Caspase-3 Inhibitor, Z-D(OMe)-E(OMe)-VD(OMe)-FMK; Caspase-4 Inhibitor, Z-LE(OMe)VD(OMe)-FMK; Caspase-5 Inhibitor, Z-WE(OMe)HD(OMe)-FMK; Caspase-6 Inhibitor, Z-VE(OMe)ID(OMe)-FMK; Caspase-8 Inhibitor, Z-IE(OMe)TD(OMe)-FMK ; Caspase-9 Inhibitor, Z-LE(OMe)HD(OMe)-FMK; Caspase-10 Inhibitor, Z-AE(OMe)VD(OMe)-FMK; Caspase-13 Inhibitor, Z-LE(OMe)E(OMe)D(OMe)-FMK, pan Caspase Inhibitor, Z-VAD(OMe)-FMK and the negatuve control, Z-FA-FMK.
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Structure Available
No
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Salt Form
No
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Molecular Formula
See under the individual product
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Molecular Weight
See under the individual product
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Cell Permeable
Yes
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Purity
See under the individual product
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Handling
Protect from air, light and moisture
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Tag Line
Caspase family inhibitors
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
12 months
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SMILES
N/A
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InChi
184(299)230-129(56-66-162(276)277)181(296)236-135(73-98(7)8)187(302)247-
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InChi Key
N/A
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MSDS Available
Yes
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Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
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