anti-IL-1 alpha Antibody, Monoclonal
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Catalog number48-735
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PricePlease ask
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Size0.05 mL
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Gene infoInterleukin 1 alpha is synthesized as a 31 kDa promolecule that does not contain a signal sequence. Following proteolytic cleavage, the mature 17 kDa molecule is released as a result of cell injury or apoptosis. IL-1 alpha stimulates bone osteoclast activity, has a role in the modulation of extracellular fluid calcium homeostasis and apoptosis, activates T and B lymphocytes and NK cells, and functions in development. Movement of the IL-1 alpha promolecule to the nucleus in response to endotoxin where it augments transcription of proinflammatory genes has also been documented.
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Gene namesIL1A, Hematopoietin-1, IL-1 alpha, IL1, IL1-ALPHA, IL1 Alpha, Interleukin-1 alpha, IL-1A, IL1F1, Pro-interleukin-1-alpha, Preinterleukin 1 alpha, Interleukin 1, alpha
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Antibodie s labelunlabelled serum
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PurityProtein A Column
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Ab raised inMouse
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TypeMonoclonal
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ImmunoglobulinIgG2a
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AntigenIL - 1 alpha monoclonal antibody was made against Ni-NTA purified recombinant human IL-1alpha expressed in E. Coli strain BL21 (DE3)
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceIL-1 alpha antibody can be used in ELISA, and immunohistochemistry starting at 20 ug/mL.
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Suspention pH azidePBS, pH 7.4, 0.03% sodium azide.
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Keep atStore IL-1 alpha antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
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Works withHuman
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Omim nr124297
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Ncbi nrP01583
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Vial with antibodyin solution
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NCBI GENE nr3552
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GENE symbolIL1A
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Antigene nameinterleukin 1, alpha
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SourceHomo sapiens
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Protein nrP01583
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DescriptionThe anti-IL-1 alpha Antibody, Monoclonal is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GeneThe Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translationanticorps
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Gene target
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Gene symbolIL1A, IL1B, IL1F10, IL36B, IL36A, IL19, IL17F, IL36G, IL25, IL22
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Short nameanti-IL-1 alpha Antibody, Monoclonal
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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Alternative nameAntibody toIL-1 a (antibody to-), monoclonal
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 alpha
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 beta
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 family member 10
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Synonyms gene name
- interleukin 1 family, member 10 (theta)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 beta
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 8 (eta)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 alpha
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 6 (epsilon)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 19
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-03-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 17F
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-03-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 25
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Synonyms gene
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Synonyms gene name
- interleukin 17E
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-01-26
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Pubmed identfication
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 22
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
