CZC-54252 hydrochloride

• Catalog number
  9567-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  N-[-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride
• Description
  CZC-54252 is a potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) (IC₅₀ values are 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively). CZC-54252 attenuates neuronal injury induced by LRRK2-G2019S
• CAS Number
  1191911-27-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₂₅ClN₆O₄S.HCl
• Molecular Weight
  541.45
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent leucine-rich repeat kinase 2 (LRRK2) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  90488950
• PubChem CID Link
• SMILES
  COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl.Cl
• InChi
  InChI=1S/C22H25ClN6O4S.ClH/c1-32-20-13-15(29-9-11-33-12-10-29)7-8-19(20)26-22-24-14-16(23)21(27-22)25-17-5-3-4-6-18(17)28-34(2,30)31;/h3-8,13-14,28H,9-12H2,1-2H3,(H2,24,25,26,27);1H
• InChi Key
  KWCBHUPLQMUKAF-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  CZC-54252   hydrochloride  
• Short name
  CZC-54252 hydrochloride
• Alternative name
  CZC-54252 hydrochloride

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