CZC 54252 Hydrochloride,LRRK2 inhibitor
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Catalog numberSIH-439-25MG
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PricePlease ask
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Size25 mg
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Research Area sCell Signaling
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CategorySmall Molecules
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Product TypeInhibitor
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CAS No1191911-27-9
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MolecularFormulaC22H26Cl2N6O4S
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Molecular Weight541.5
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Purity>98%
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SolubilitySoluble to 100 mM in DMSO
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AppearanceYellow solid
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Storage Temperature-20°C
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Shipping TemperatureShipped Ambient
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolLRRK2-DT, LRRK2
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Short nameCZC 54252 Hydrochloride LRRK2 inhibitor
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Alternative nameCZC 54252 Hydrochloride,leucine-rich repeat kinase 2 suppressor
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Alternative to gene targetleucine-rich repeat kinase 2, LRRK2 and IDBG-27257 and ENSG00000188906 and 120892, transferase activity, Extracellular, Lrrk2 and IDBG-175625 and ENSMUSG00000036273 and 66725, LRRK2 and IDBG-633456 and ENSBTAG00000016260 and 535652
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Gene info
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Identity
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Gene
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Long gene nameLRRK2 divergent transcript
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Locus
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Discovery year2019-08-16
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Entrez gene record
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene nameleucine rich repeat kinase 2
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Synonyms gene
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Synonyms gene name
- Parkinson disease (autosomal dominant) 8
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-10-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Armadillo like helical domain containing
- ROCO family
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VEGA ID
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Locus Specific Databases